M1574
Miglitol
Synonym(s):
1-(2-Hydroxyethyl)-2-(hydroxymethyl)piperidine-3,4,5-triol
Sign Into View Organizational & Contract Pricing
All Photos(1)
About This Item
Empirical Formula (Hill Notation):
C8H17NO5
CAS Number:
Molecular Weight:
207.22
EC Number:
UNSPSC Code:
12352205
NACRES:
NA.25
Recommended Products
biological source
synthetic (organic)
Quality Level
assay
≥98% (HPLC)
form
powder
mp
142-147 °C
solubility
water: 5 mg/mL, clear, colorless to faintly yellow
storage temp.
room temp
SMILES string
N1([C@@H]([C@H]([C@@H]([C@H](C1)O)O)O)CO)CCO
InChI
1S/C8H17NO5/c10-2-1-9-3-6(12)8(14)7(13)5(9)4-11/h5-8,10-14H,1-4H2/t5-,6+,7-,8-/m1/s1
InChI key
IBAQFPQHRJAVAV-ULAWRXDQSA-N
General description
Miglitol is an alpha-glucosidase inhibitor used as a glucose-lowering drug in diabetes research.
Storage Class
11 - Combustible Solids
wgk_germany
WGK 1
flash_point_f
Not applicable
flash_point_c
Not applicable
Choose from one of the most recent versions:
Already Own This Product?
Find documentation for the products that you have recently purchased in the Document Library.
Customers Also Viewed
Kazutaka Aoki et al.
Acta diabetologica, 49(3), 225-230 (2011-09-08)
We recently reported that the administration of miglitol alone just before breakfast improved postprandial hyperglycemia and increased active glucagon-like peptide-1 (GLP-1) levels after lunch in men without diabetes. Miglitol and dipeptidyl peptidase-4 inhibitors, such as sitagliptin, enhance plasma active GLP-1
Takuo Emoto et al.
The American journal of cardiology, 109(1), 42-46 (2011-09-29)
Repeated postprandial hyperglycemia may play an important role in the development of atherosclerosis by suppressing vascular endothelial function. Although miglitol suppresses the elevation of blood glucose levels shortly after a meal more than other α-glucosidase inhibitors, the effect of 3-month
Kyra Jones et al.
Bioorganic & medicinal chemistry, 19(13), 3929-3934 (2011-06-15)
Inhibition of intestinal α-glucosidases and pancreatic α-amylases is an approach to controlling blood glucose and serum insulin levels in individuals with Type II diabetes. The two human intestinal glucosidases are maltase-glucoamylase and sucrase-isomaltase. Each incorporates two family 31 glycoside hydrolases
Kenichi Matsuura et al.
Diabetes technology & therapeutics, 14(5), 423-429 (2012-02-10)
We compared the effects of miglitol as an add-on to bolus insulin and dose-intensified bolus insulin on postprandial glycemic excursions by continuous glucose monitoring (CGM). The glucose levels of 21 type 2 diabetes patients admitted for glycemic control were monitored
Hongxiang Hui et al.
Chinese medicine, 4, 11-11 (2009-06-16)
Conventional drugs treat diabetes by improving insulin sensitivity, increasing insulin production and/or decreasing the amount of glucose in blood. Several herbal preparations are used to treat diabetes, but their reported hypoglycemic effects are complex or even paradoxical in some cases.
Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.
Contact Technical Service