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G0513

Sigma-Aldrich

Gly-Pro p-nitroanilide hydrochloride

≥99% (HPLC)

Synonym(s):

GP-pNA

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About This Item

Empirical Formula (Hill Notation):
C13H16N4O4 · HCl
CAS Number:
103213-34-9
Molecular Weight:
328.75
MDL number:
MFCD00058170
UNSPSC Code:
12352204
PubChem Substance ID:
24895016
NACRES:
NA.32

assay

≥99% (HPLC)

form

powder

solubility

water: 50 mg/mL, clear, faintly yellow to yellow

shipped in

wet ice

storage temp.

−20°C

SMILES string

Cl.NCC(=O)N1CCCC1C(=O)Nc2ccc(cc2)N(=O)=O

InChI

1S/C13H16N4O4.ClH/c14-8-12(18)16-7-1-2-11(16)13(19)15-9-3-5-10(6-4-9)17(20)21;/h3-6,11H,1-2,7-8,14H2,(H,15,19);1H

InChI key

VBBFIBMVFSUUBP-UHFFFAOYSA-N

Application

Gly-Pro p-nitroanilide hydrochloride has been used as a substrate in dipeptidyl peptidase-IV (DPP-IV) enzyme assay. It has also been used to determine DPP-IV inhibitory activity.

Substrates

Substrate for Dipeptidyl Peptidase IV.

Storage Class

11 - Combustible Solids

wgk_germany

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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Multifunctional biological activities of water extract of housefly larvae (Musca domestica)
Li H, et al
PharmaNutrition, 5(4), 119-126 (2017)
Chemical composition and inhibitory activities on dipeptidyl peptidase IV and pancreatic lipase of two underutilized species from the Brazilian Savannah: Oxalis cordata A. St.-Hil. and Xylopia aromatica (Lam.) Mart
Oliveira VB, et al.
Food Research International, 105, 989-995 (2018)
Monitoring of dipeptidyl peptidase-IV (DPP-IV) activity in patients with mucopolysaccharidoses types I and II on enzyme replacement therapy?Results of a pilot study
Hetmanczyk K, et al.
Clinical Biochemistry, 49(6), 458-462 (2016)
Antidiabetic evaluation of Hemionitis arifolia leaves by in vitro methods
Kumar KKR, et al.
Manipal journal of pharmaceutical sciences., 1(1), 13-20 (2015)
Yating Lu et al.
International journal of molecular sciences, 20(2) (2019-01-17)
Dipeptidyl peptidase IV (DPP-IV) inhibitors occupy a growing place in the drugs used for the management of type 2 diabetes. Recently, food components, including food-derived bioactive peptides, have been suggested as sources of DPP-IV inhibitors without side effects. Chinese black
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