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Key Documents

F3272

Sigma-Aldrich

Inulin–FITC

from dahlia tuber

Synonym(s):

Fluorescein isothiocyanate–inulin

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About This Item

MDL number:
UNSPSC Code:
12352201
NACRES:
NA.25

biological source

dahlia tuber

Quality Level

form

powder

mol wt

2,000-5,000

color

light yellow to dark yellow, to dark orange

solubility

water: soluble, clear

storage temp.

2-8°C

Application


  • Development and validation of bioengineered intestinal tubules for translational research aimed at safety and efficacy testing of drugs and nutrients.: This study employs Inulin–FITC to investigate the absorption characteristics of bioengineered intestinal models, providing critical data on gut permeability and nutrient interaction, which is crucial for pharmaceutical and nutritional research (Jochems et al., 2019).

  • Role of Vitamin D in Maintaining Renal Epithelial Barrier Function in Uremic Conditions.: Utilizes Inulin–FITC to measure the efficacy of Vitamin D in preserving renal barrier function under stress conditions, which could lead to new treatments for chronic kidney disease (Mihajlovic et al., 2017).

  • Inhibition of p38 mitogen-activated protein kinase attenuates butyrate-induced intestinal barrier impairment in a Caco-2 cell monolayer model.: This investigation highlights the role of Inulin–FITC in studying the protective effects of kinase inhibition on intestinal barriers, relevant for gastrointestinal disorder treatments (Huang et al., 2014).

  • Measurement of glomerular filtration rate in conscious mice using FITC-inulin clearance.: Demonstrates the utility of Inulin–FITC in precise, non-invasive measurements of renal function, essential for nephrology research and therapy development (Qi and Breyer, 2009).

  • PPAR gamma agonist normalizes glomerular filtration rate, tissue levels of homocysteine, and attenuates endothelial-myocyte uncoupling in alloxan induced diabetic mice.: Incorporates Inulin–FITC to assess the efficacy of a PPAR gamma agonist in diabetic nephropathy, providing insights into metabolic disease management (Rodriguez et al., 2008).

Other Notes

To gain a comprehensive understanding of our extensive range of Oligosaccharides for your research, we encourage you to visit our Carbohydrates Category page.

Storage Class

11 - Combustible Solids

wgk_germany

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable


Certificates of Analysis (COA)

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Biman B Mandal et al.
Nanotechnology, 20(35), 355101-355101 (2009-08-13)
In recent times self-assembled micellar nanoparticles have been successfully employed in tissue engineering for targeted drug delivery applications. In this review, silk sericin protein from non-mulberry Antheraea mylitta tropical tasar silk cocoons was blended with pluronic F-127 and F-87 in
M A Storr et al.
Neurogastroenterology and motility : the official journal of the European Gastrointestinal Motility Society, 22(7), 787-796 (2010-02-26)
Cannabinoid type 1 (CB(1)) receptors are involved in the regulation of gastrointestinal (GI) motility and secretion. Our aim was to characterize the roles of the CB(1) receptor on GI motility and secretion in vitro and in vivo by using different
N T Baker et al.
Microbial pathogenesis, 49(5), 260-272 (2010-07-06)
Campylobacter fetus is a recognized pathogen of cattle and sheep, though human infection has also been reported. Ingestion of contaminated food or water is a proposed route of transmission for both humans and animals. The subsequent detection of the organism
Chunhua Jin et al.
Hypertension (Dallas, Tex. : 1979), 53(6), 1048-1053 (2009-05-13)
Studies were designed to determine the effects of increases of renal perfusion pressure on the production of hydrogen peroxide (H(2)O(2)) and NO(2)(-)+NO(3)(-) within the renal outer medulla. Sprague-Dawley rats were studied with either the renal capsule intact or removed to
Paul Brakeman et al.
Biomicrofluidics, 10(6), 064106-064106 (2016-12-06)
Most current microfluidic cell culture systems are integrated single use devices. This can limit throughput and experimental design options, particularly for epithelial cells, which require significant time in culture to obtain a fully differentiated phenotype. In addition, epithelial cells require

Articles

Additional information about FITC-labelled polysaccarides including FITC-Dextran, FITC-DEAE-dextran (FDD), FITC-carboxymethyl-dextran (FCM-Dextran). This page discusses the impact of weight-average molecular weight on the respective molecule dimensions and other physical properties

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