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91462

Sigma-Aldrich

Kollisolv® PEG E 300

Synonym(s):

Poly(ethylene glycol), Lutrol E 300, Macrogol 300, Polyethylene glycol 300, PEG

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About This Item

Linear Formula:
H(OCH2CH2)nOH
CAS Number:
25322-68-3
MDL number:
MFCD00081839
UNSPSC Code:
12352104
NACRES:
NA.25

form

liquid

mol wt

average Mw 285-315 g/mol (from OH-value (56100*2)/OHZ)

impurities

reducing substances, complies
≤0.1% sulfated ash
≤0.25% ethylene glycol and diethylene glycol (sum)
≤1 ppm ethylene oxide
≤1 ppm lead (verified on random samples only)
≤1.0% water
≤10 ppm dioxan
≤15 ppm formaldehyde
≤5 ppm heavy metals (verified on random samples only)
0.5 g acetic acid (per 100 g)
620 ppm ethylene oxide

pH

4.5-7.0 (50 g/L)

viscosity

80-105 mPa.s(20 °C) (5.4-6.4 CS (98.9°C))

hydroxyl value

340‑394 mg KOH/g

solubility

H2O: 10%, clear, colorless

suitability

complies for acidity or alkalinity

SMILES string

C(CO)O

InChI

1S/C2H6O2/c3-1-2-4/h3-4H,1-2H2

InChI key

LYCAIKOWRPUZTN-UHFFFAOYSA-N

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Application

Kollisolv polyethylene glycols are used as thickening agents and gel binders in the pharmaceutical industry.
This research grade product is intended for use in R&D and development only.

Other Notes

The PEG E grades of Kollisolv are polyethylene glycols (macrogols) of different molecular weights.

Legal Information

Kollisolv is a registered trademark of BASF

Storage Class

10 - Combustible liquids

wgk_germany

WGK 1

flash_point_f

428.0 °F - closed cup

flash_point_c

220.00 °C - closed cup

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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Scott N Furlan et al.
Science translational medicine, 7(315), 315ra191-315ra191 (2015-11-27)
Graft-versus-host disease (GVHD) is the most common complication of hematopoietic stem cell transplant (HCT). However, our understanding of the molecular pathways that cause this disease remains incomplete, leading to inadequate treatment strategies. To address this, we measured the gene expression
D D Smyth et al.
Cardiovascular drugs and therapy, 4(1), 297-300 (1990-02-01)
Previous studies have demonstrated that Separan AP-30, a drag-reducing polymer, significantly decreased the formation of atherosclerotic plaques in rabbits fed a high-cholesterol diet. Furthermore, Separan AP-273, a polymer similar to but longer than Separan AP-30, markedly increased cardiac output in
M Patel Geeta et al.
Current drug delivery, 6(2), 159-165 (2009-05-20)
Carbamazepine indicated for the control of epilepsy, undergoes extensive hepatic first-pass metabolism after oral administration. A vaginal dosage form of carbamazepine is not commercially available. Conventional suppository having poor retention in the vaginal tract, as they are removed in a
P I Polimeni et al.
Journal of cardiovascular pharmacology, 14(3), 374-380 (1989-09-01)
The acute hemodynamic effects of an intravenously (i.v.) injected poly(ethylene oxide), Polyox WSR N-60K (dose 50 mg/kg), were studied in the open-chest rat anesthetized with sodium pentobarbital. The injectate is one of four drag-reducing polymers known to augment in vitro
I L Konorova et al.
Patologicheskaia fiziologiia i eksperimental'naia terapiia, (4)(4), 7-9 (1991-07-01)
The search for antiaggregatory compounds is undertaken, as a rule, under in vitro conditions which do not reflect the dynamics of the real process. The present work deals with study of the peculiarities of the development of the collagen induced

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