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Key Documents

76437

Sigma-Aldrich

Pentaethylene glycol monododecyl ether

BioXtra, ≥98.0% (GC)

Synonym(s):

C12E5, Dodecyl pentaethylene glycol ether, Dodecylpentaglycol, Polyoxyethylene (5) lauryl ether

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About This Item

Linear Formula:
CH3(CH2)11(OCH2CH2)5OH
CAS Number:
Molecular Weight:
406.60
Beilstein/REAXYS Number:
1797921
EC Number:
MDL number:
UNSPSC Code:
12161900
PubChem Substance ID:
NACRES:
NA.25

description

non-ionic

Quality Level

product line

BioXtra

assay

≥98.0% (GC)

form

semisolid

mol wt

406.60 g/mol

technique(s)

drug transporter assay: suitable

density

0.963 g/mL at 20 °C (lit.)

cation traces

Ca: ≤50 mg/kg
Cd: ≤50 mg/kg
Co: ≤50 mg/kg
Cr: ≤50 mg/kg
Cu: ≤50 mg/kg
Fe: ≤50 mg/kg
K: ≤50 mg/kg
Mg: ≤50 mg/kg
Mn: ≤50 mg/kg
Na: ≤50 mg/kg
Ni: ≤50 mg/kg
Pb: ≤50 mg/kg
Zn: ≤50 mg/kg

SMILES string

CCCCCCCCCCCCOCCOCCOCCOCCOCCO

InChI

1S/C22H46O6/c1-2-3-4-5-6-7-8-9-10-11-13-24-15-17-26-19-21-28-22-20-27-18-16-25-14-12-23/h23H,2-22H2,1H3

InChI key

LAPRIVJANDLWOK-UHFFFAOYSA-N

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Application

<ul>
<li><strong>Coadsorption of a Monoclonal Antibody and Nonionic Surfactant at the SiO(2)/Water Interface:</strong> This study demonstrates the coadsorption properties of Pentaethylene glycol monododecyl ether with monoclonal antibodies, offering significant implications for biopharmaceutical formulations to improve drug stability and delivery (Lu et al., 2018).</li>
<li><strong>Water-Resistant Surface Modification of Hydrophobic Polymers with Water-Soluble Surfactant Additives:</strong> This research showcases the effectiveness of Pentaethylene glycol monododecyl ether in modifying hydrophobic polymer surfaces to make them water-resistant, pointing to its utility in various industrial and coating applications (Thompson et al., 2021).</li>
<li><strong>Synergistic Role of Temperature and Salinity in Aggregation of Nonionic Surfactant-Coated Silica Nanoparticles:</strong> Highlights the use of Pentaethylene glycol monododecyl ether in nanoparticle stabilization, particularly under varying thermal and saline conditions, beneficial for tailored drug delivery systems and environmental applications (Bharti et al., 2023).</li>
</ul>

pictograms

CorrosionExclamation mark

signalword

Danger

Hazard Classifications

Eye Dam. 1 - Skin Irrit. 2 - STOT SE 3

target_organs

Respiratory system

Storage Class

10 - Combustible liquids

wgk_germany

WGK 2

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type ABEK (EN14387) respirator filter


Certificates of Analysis (COA)

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Thorsten Pieper et al.
The Journal of chemical physics, 127(16), 165102-165102 (2007-11-06)
Biological membranes consist of lipid bilayers with liquid-ordered and liquid-disordered phases. It is believed that cholesterol controls the size of the microdomains in the liquid-ordered phase and thereby affects the mobility as well as the permeability of the membrane. We
Y Kawabata et al.
The Journal of chemical physics, 147(3), 034905-034905 (2017-07-25)
Shear-induced multilamellar vesicle (MLV) formation has been studied by coupling the small-angle neutron scattering (SANS) technique with neutron spin echo (NSE) spectroscopy. A 10% mass fraction of the nonionic surfactant pentaethylene glycol dodecyl ether (C
U Sivars et al.
Journal of chromatography. B, Biomedical applications, 680(1-2), 43-53 (1996-05-17)
The study includes partitioning of proteins in aqueous two-phase systems consisting of the polymer dextran and the non-ionic surfactant C12E5 (pentaethylene glycol mono-n-dodecyl ether). In this system a micelle-enriched phase is in equilibrium with a polymer-enriched phase. Charges can be
Anita I Kishore et al.
Nucleic acids research, 33(18), e164-e164 (2005-10-29)
Analysis of the 13C isotopic labeling patterns of nucleoside monophosphates (NMPs) extracted from Escherichia coli grown in a mixture of C-1 and C-2 glucose is presented. By comparing our results to previous observations on amino acids grown in similar media
S Bulut et al.
The European physical journal. E, Soft matter, 27(3), 261-273 (2008-10-31)
We present a comprehensive study of the concentration-induced growth of nonionic wormlike micelles in dilute solutions, below the overlap concentration, where we combine static and dynamic light scattering and NMR self-diffusion. The data are analyzed in detail in terms of

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