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46943

Sigma-Aldrich

Fluorescein dilaurate

suitable for fluorescence, ≥97.0% (HPCE)

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About This Item

Empirical Formula (Hill Notation):
C44H56O7
CAS Number:
7308-90-9
Molecular Weight:
696.91
Beilstein/REAXYS Number:
6034843
EC Number:
230-764-2
MDL number:
MFCD00038409
UNSPSC Code:
12352106
PubChem Substance ID:
57650888
NACRES:
NA.32

assay

≥97.0% (HPCE)

form

powder

solubility

ethanol: soluble

fluorescence

λex 490 nm; λem 514 nm in 0.1 M Tris pH 8.0 (esterase)

suitability

suitable for fluorescence

SMILES string

CCCCCCCCCCCC(=O)Oc1ccc2c(Oc3cc(OC(=O)CCCCCCCCCCC)ccc3C24OC(=O)c5ccccc45)c1

InChI

1S/C44H56O7/c1-3-5-7-9-11-13-15-17-19-25-41(45)48-33-27-29-37-39(31-33)50-40-32-34(49-42(46)26-20-18-16-14-12-10-8-6-4-2)28-30-38(40)44(37)36-24-22-21-23-35(36)43(47)51-44/h21-24,27-32H,3-20,25-26H2,1-2H3

InChI key

MYTRGBGGRICZGN-UHFFFAOYSA-N

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Application

Fluorescein dilaurate is suitable as fluorogenic substrate for esterases/lipases and used in the pancreolauryl test for chronic pancreatitis.

Storage Class

11 - Combustible Solids

wgk_germany

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)

Certificates of Analysis (COA)

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J E Domínguez-Muñoz et al.
Clinical chemistry, 44(4), 869-875 (1998-05-15)
The serum pancreolauryl test has limited sensitivity for detecting mild pancreatic insufficiency. The aim of this study was to optimize the serum pancreolauryl test so as to increase the probability of positive results in patients with chronic pancreatitis. The study
J E Domínguez-Muñoz et al.
The American journal of gastroenterology, 88(8), 1237-1241 (1993-08-01)
Indirect pancreatic function tests are frequently used in the clinical routine as complementary tools for the diagnosis of chronic pancreatitis (CP) because of their noninvasiveness and simplicity. We analyzed the clinical efficacy and routine application of a modified serum pancreolauryl
A perspective on the use of tubeless pancreatic function tests in diagnosis.
E P DiMagno
Gut, 43(1), 2-3 (1998-10-15)
F M Stevens et al.
Journal of clinical pathology, 50(12), 1001-1004 (1998-03-28)
To determine the frequency of abnormal pancreolauryl tests in untreated and treated adults with coeliac disease and to see whether abnormalities in treated coeliac patients correlate with the degree of recovery of intestinal morphology or brush border enzyme activity. Pancreolauryl
F Seibold et al.
Journal of clinical gastroenterology, 22(3), 202-206 (1996-04-01)
Pancreatic autoantibodies (PABs) are found in 31% of patients with Crohn's disease (CD), but they do not correlate with the activity of intestinal disease or the incidence of acute pancreatitis. Exocrine pancreatic insufficiency has been observed in patients with CD.
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