77234

Perchloric acid

puriss. p.a., ACS reagent, packed in coated, shock- and leak-protected glass bottle, ≥60% (T)

• Synonym(s): PCA
• Linear Formula: HClO₄
• CAS Number: 7601-90-3
• Molecular Weight: 100.46
• MDL number: MFCD00011325
• UNSPSC Code: 12352106
• PubChem Substance ID: 329767556
• NACRES: NA.21

Properties

• grade: ACS reagent; puriss. p.a.
• form: liquid
• quality: packed in coated, shock- and leak-protected glass bottle
• concentration: ≥60% (T)
• impurities: ≤0.00005% free chlorine (Cl); ≤0.001% total nitrogen (N)
• ign. residue: ≤0.003% (as SO₄)
• density: 1.670 g/cm³
• anion traces: chlorate (ClO₃^-): ≤10 mg/kg; chloride (Cl^-): ≤3 mg/kg; phosphate, silicate (as SiO₂): ≤5 mg/kg; sulfate (SO₄^2-): ≤10 mg/kg
• cation traces: Ag: ≤0.1 mg/kg; Al: ≤0.05 mg/kg; As: ≤0.05 mg/kg; Ba: ≤0.02 mg/kg; Bi: ≤0.1 mg/kg; Ca: ≤0.5 mg/kg; Cd: ≤0.05 mg/kg; Co: ≤0.05 mg/kg; Cu: ≤0.1 mg/kg; Fe: ≤1 mg/kg; K: ≤0.1 mg/kg; Li: ≤0.02 mg/kg; Mg: ≤0.5 mg/kg; Mn: ≤0.02 mg/kg; Mo: ≤0.05 mg/kg; Ni: ≤0.1 mg/kg; Pb: ≤0.05 mg/kg; Sr: ≤0.02 mg/kg; Tl: ≤0.05 mg/kg; Zn: ≤0.1 mg/kg
• SMILES string: OCl(=O)(=O)=O
• InChI: 1S/ClHO4/c2-1(3,4)5/h(H,2,3,4,5)
• InChI key: VLTRZXGMWDSKGL-UHFFFAOYSA-N

Description

General description

Perchloric acid (HClO₄), an oxygen acid of chlorine, is a colorless liquid. It is strongly acidic in nature. Hydrates of perchloric acid are obtained on its dissolution in water.

Application

• Development of the Chromatographic Method for Simultaneous Determination of Azaperone and Azaperol in Animal Kidneys and Livers.: This study used perchloric acid for the sample preparation in HPLC analysis, which is crucial for veterinary drug residue analysis in food safety research (Koska and Kubalczyk, 2022).


• Development of a High Performance Liquid Chromatography with Diode Array Detector (HPLC-DAD) Method for Determination of Biogenic Amines in Ripened Cheeses.: The research utilized perchloric acid for sample deproteinization, demonstrating its application in food chemistry for the quality control of dairy products (Pawul-Gruba et al., 2022).


• Vibrational and impedance analysis of the beta-stannic acid samples plasticized by perchloric acid.: This study employed perchloric acid in the plasticization process, essential for materials science research on improving the properties of beta-stannic acid (Karelin et al., 2022).


• Measurement of tigecycline in dried blood spots by LC-MS/MS and comparison tigecycline concentrations between whole blood and plasma.: Perchloric acid was used in the sample preparation for LC-MS/MS analysis, crucial for pharmacokinetic studies in clinical research (Yan et al., 2023).


• SiO(2)-supported HClO(4) catalyzed synthesis of (Z)-thiazolylhydrazonoindolin-2-ones and their electrochemical properties.: The research highlights the use of perchloric acid as a catalyst, demonstrating its application in organic synthesis and electrochemistry (Shaik et al., 2022).

Other Notes

Reagent for the decomposition of metals and organic compounds (danger of explosions)

Safety Information

• pictograms: GHS03,GHS08,GHS05,GHS07
• signalword: Danger
• hcodes: H271,H290,H302,H314,H373
• pcodes: P210 - P280 - P301 + P312 - P303 + P361 + P353 - P305 + P351 + P338 - P314
• Hazard Classifications: Acute Tox. 4 Oral - Eye Dam. 1 - Met. Corr. 1 - Ox. Liq. 1 - Skin Corr. 1A - STOT RE 2
• target_organs: Thyroid
• Storage Class: 5.1A - Strongly oxidizing hazardous materials
• wgk_germany: WGK 1