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Y0001079

Benserazide for peak identification

European Pharmacopoeia (EP) Reference Standard

Synonym(s):

Benserazide hydrochloride, DL-Serine 2-(2,3,4-trihydroxybenzyl)hydrazide hydrochloride

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About This Item

Empirical Formula (Hill Notation):
C10H15N3O5 · HCl
CAS Number:
14919-77-8
Molecular Weight:
293.70
MDL number:
MFCD00078571
UNSPSC Code:
41116107
PubChem Substance ID:
329831250
NACRES:
NA.24

grade

pharmaceutical primary standard

manufacturer/tradename

EDQM

application(s)

pharmaceutical (small molecule)

format

neat

storage temp.

2-8°C

SMILES string

Cl.NC(CO)C(=O)NNCc1ccc(O)c(O)c1O

InChI

1S/C10H15N3O5.ClH/c11-6(4-14)10(18)13-12-3-5-1-2-7(15)9(17)8(5)16;/h1-2,6,12,14-17H,3-4,11H2,(H,13,18);1H

InChI key

ULFCBIUXQQYDEI-UHFFFAOYSA-N

Gene Information

human ... DDC(1644)

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General description

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia.For further information and support please go to the website of the issuing Pharmacopoeia.

Application

Benserazide for peak identification EP Reference standard, intended for use in laboratory tests only as specifically prescribed in the European Pharmacopoeia.

Biochem/physiol Actions

Inhibitor of L-aromatic amino acid decarboxylase.

Packaging

The product is delivered as supplied by the issuing Pharmacopoeia. For the current unit quantity, please visit the EDQM reference substance catalogue.

Other Notes

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Yong Wang et al.
Synapse (New York, N.Y.), 68(8), 332-343 (2014-03-07)
l-3,4-Dihydroxyphenylalanine (L-DOPA) is the most widely used drug for the treatment of Parkinson's disease. Unfortunately, chronic administration of this dopamine precursor causes L-DOPA-induced dyskinesia (LID), which is a debilitating complication whose pathogenesis remains unclear. In this study, we compared gene
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