PHR8948

6-epi-Doxycycline HCl

certified reference material, pharmaceutical secondary standard

• Synonym(s): 2-Naphthacenecarboxamide, 4-(dimethylamino)-1,4,4a,5,5a,6,11,12a-octahydro-3,5,10,12,12a-pentahydroxy-6-methyl-1,11-dioxo-, 6-epimer, monohydrochloride.
• Empirical Formula (Hill Notation): C₂₂H₂₄N₂O₈ · HCl
• CAS Number: 41411-66-9
• Molecular Weight: 480.90
• UNSPSC Code: 41116107
• NACRES: NA.24

Properties

• grade: certified reference material; pharmaceutical secondary standard
• Quality Level: 300
• API family: doxycycline
• packaging: pkg of 50MG
• application(s): pharmaceutical
• storage temp.: -10 to -25°C

Description

General description

Pharmaceutical secondary standards for application in quality control provide pharma laboratories and manufacturers with a convenient and cost-effective alternative to the preparation of in-house working standards.

The Oligonucleotide HPLC Performance Standard Mix (Oligo-6) is a calibration standard with carefully selected oligonucleotides to test and monitor changes in HPLC and LC/MS Systems. The difference in the selectivity of the oligonucleotides make it useful for most chromatographic modes including Ion Pairing Reversed Phase, Ion Exchange and HILIC Methods.

The oligonucleotides in the mix are dried and between 12-33 NT that makes it a suitable tool alongside development and quality control of therapeutics like antisense oligonucleotides, small interfering RNAs, and aptamers.

Components

Sequence 1, 12 NT, 3588.4 Da

Sequence 2, 12 NT, 4158.0 Da

Sequence 3, 25 NT, 7580.9 Da

Sequence 4, 33 NT, 10014.4 Da

Sequence 5, 20 NT, 6117.0 Da

Sequence 6, 15 NT, 4395.9 Da

Application

This Oligonucleotide Standard Mix are used for:

• System suitability and creation of control charts
• Method transfer and troubleshooting
• Monitoring of HPLC Column life span IPRP-HPLC, IEX HPLC, HILIC, LCMS.

Other Notes

More information regarding the use of this product is available on the certificate of analysis and technical note.

Safety Information

• pictograms: GHS08,GHS07
• signalword: Warning
• hcodes: H302,H361d
• pcodes: P202 - P264 - P270 - P280 - P301 + P312 - P308 + P313
• Hazard Classifications: Acute Tox. 4 Oral - Repr. 2
• Storage Class: 11 - Combustible Solids
• wgk_germany: WGK 3
• flash_point_f: Not applicable
• flash_point_c: Not applicable