PHL80465

Gramine

phyproof^® Reference Substance

• Synonym(s): 3-(Dimethylaminomethyl)indole, Donaxine, NSC 16892
• Empirical Formula (Hill Notation): C₁₁H₁₄N₂
• CAS Number: 87-52-5
• Molecular Weight: 174.24
• Beilstein/REAXYS Number: 140521
• MDL number: MFCD00005629
• UNSPSC Code: 41116107

Properties

• grade: primary reference standard
• product line: phyproof^® Reference Substance
• assay: ≥98.0% (HPLC)
• manufacturer/tradename: PhytoLab
• mp: 132-134 °C (lit.)
• format: neat
• SMILES string: CN(C)Cc1c[nH]c2ccccc12
• InChI: 1S/C11H14N2/c1-13(2)8-9-7-12-11-6-4-3-5-10(9)11/h3-7,12H,8H2,1-2H3
• InChI key: OCDGBSUVYYVKQZ-UHFFFAOYSA-N

Description

General description

This substance is a primary reference substance with assigned absolute purity (considering chromatographic purity, water, residual solvents, inorganic impurities). The exact value can be found on the certificate. Produced by PhytoLab GmbH & Co. KG

Application

Reactant for preparation of:

• Dopamine D2 receptor antagonists
• Anti-malarial drugs
• 5-indolyl-Mannich bases
• Proliferation inhibitors
• Inhibitors of human mast cell chymase
• Preparation of DL-tryptophan
• Potential detoxification inhibitors of the crucifer phytoalexin brassinin
• 3-vinylindoles
• Serotonin 5-HT6 receptor ligand templates
• Selective protein kinase c delta (PKCδ) down regulators

Legal Information

phyproof is a registered trademark of PhytoLab GmbH & Co. KG

Safety Information

• pictograms: GHS07
• signalword: Warning
• hcodes: H302 + H312
• pcodes: P264 - P280 - P301 + P312 - P302 + P352 + P312 - P362 + P364 - P501
• Hazard Classifications: Acute Tox. 4 Dermal - Acute Tox. 4 Oral
• Storage Class: 11 - Combustible Solids
• wgk_germany: WGK 3
• flash_point_f: 332.6 °F
• flash_point_c: 167 °C