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P2125

Supelco

D-Pantethine

analytical standard

Synonym(s):

Bis(N-pantothenylamidoethyl) disulfide, LBF factor, Pantethein oxidized form

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About This Item

Empirical Formula (Hill Notation):
C22H42N4O8S2
CAS Number:
16816-67-4
Molecular Weight:
554.72
EC Number:
240-842-8
MDL number:
MFCD00151211
UNSPSC Code:
41116107
PubChem Substance ID:
329820118
NACRES:
NA.24

biological source

synthetic (organic)

Quality Level

100

grade

analytical standard

assay

≥90%

technique(s)

HPLC: suitable
gas chromatography (GC): suitable

color

white

application(s)

forensics and toxicology
veterinary
vitamins, nutraceuticals, and natural products

format

neat

storage temp.

2-8°C

SMILES string

CC(C)(CO)[C@@H](O)C(=O)NCCC(=O)NCCSSCCNC(=O)CCNC(=O)[C@H](O)C(C)(C)CO

InChI

1S/C22H42N4O8S2/c1-21(2,13-27)17(31)19(33)25-7-5-15(29)23-9-11-35-36-12-10-24-16(30)6-8-26-20(34)18(32)22(3,4)14-28/h17-18,27-28,31-32H,5-14H2,1-4H3,(H,23,29)(H,24,30)(H,25,33)(H,26,34)/t17-,18-/m0/s1

InChI key

DJWYOLJPSHDSAL-ROUUACIJSA-N

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Application

Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.

Storage Class

11 - Combustible Solids

wgk_germany

WGK 2

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)

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Certificates of Analysis (COA)

Lot/Batch Number
SLCK5148
SLCB6925
SLBQ2041V
SLBL3300V
SLBH5121V

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Cysteamine ~95%

Sigma-Aldrich

M9768

Cysteamine

H Matsushima et al.
Experimental eye research, 64(3), 387-395 (1997-03-01)
This study of lens protein composition found that some cytoskeletal proteins were degraded during the earliest stages of cataract formation. Cataract was induced in 13-14 day old rats by a single subcutaneous injection of sodium selenite (19 mumol kg-1). By
J J Harding
Drugs & aging, 18(7), 473-486 (2001-08-03)
Cataract is the major cause of blindness and of visual impairment worldwide, so its prevention is of the greatest importance. At present no drug therapy is licensed for use in the UK or the US, so the only treatment for
M J Webster
European journal of applied physiology and occupational physiology, 77(6), 486-491 (1998-07-03)
The purpose of this study was to investigate the physiological and performance responses to supplementation with allithiamin and pantethine. On two separate occasions, six highly trained cyclists [maximum O2 consumption or VO2max 61.8 (2.1) ml x kg(-1) x min(-1)] performed
M F McCarty
Medical hypotheses, 56(3), 314-317 (2001-05-22)
Pantethine is a versatile and well-tolerated hypolipidemic agent whose efficacy in this regard appears to be mediated by its catabolic product cystamine, a nucleophile which avidly attacks disulfide groups. An overview of pantethine research suggests that the hypotriglyceridemic activity of
John A Rumberger et al.
Nutrition research (New York, N.Y.), 31(8), 608-615 (2011-09-20)
Safety and efficacy of a biologically active derivative of vitamin B(5) (pantethine) on total cholesterol (TC) and low-density lipoprotein cholesterol (LDL-C) metabolism was studied in North American subjects at conventional low to moderate cardiovascular disease (CVD) risk. A total of
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