P1004
Polymyxin B sulfate salt
Synonym(s):
Polymixin, Polymixin B, Polymixin B sulfate
About This Item
Recommended Products
biological source
Pseudomonas aeruginosa
Quality Level
form
powder
storage condition
(Tightly closed. Dry. )
solubility
water: 50 mg/mL
antibiotic activity spectrum
Gram-negative bacteria
fungi
mode of action
cell membrane | interferes
storage temp.
2-8°C
SMILES string
O=C(C(NC(C(CCN)NC(CCCCC(C)CC)=O)=O)C(C)O)NC(CCN)C(NC(CCNC(C(NC(C(NC(C(CCN)N1)=O)CCN)=O)C(O)C)=O)C(NC(CCN)C(NC(CC2=CC=CC=C2)C(NC(CC(C)C)C1=O)=O)=O)=O)=O.O=S(O)(O)=O
InChI
1S/C48H82N16O13.H2O4S/c1-27(2)24-37-47(76)59-32(11-19-52)41(70)56-31(10-18-51)43(72)61-35(14-22-65)39(68)54-21-13-34(45(74)57-33(12-20-53)44(73)64-38(48(77)63-37)25-28-6-4-3-5-7-28)60-42(71)30(9-17-50)58-46(75)36(15-23-66)62-40(69)29(8-16-49)55-26-67;1-5(2,3)4/h3-7,26-27,29-38,65-66H,8-25,49-53H2,1-2H3,(H,54,68)(H,55,67)(H,56,70)(H,57,74)(H,58,75)(H,59,76)(H,60,71)(H,61,72)(H,62,69)(H,63,77)(H,64,73);(H2,1,2,3,4)
InChI key
HNDFYNOVSOOGDU-UHFFFAOYSA-N
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General description
Application
- in human aortic endothelial cells (HAEC) cell culture to exclude potential endotoxin contamination in recombinant adiponectin
- in the analysis of the isolates
- in endotoxin-neutralizing activity of α-amylase (AmyI-1)-18 (LAL assay)
Biochem/physiol Actions
Antimicrobial spectrum: Has bactericidal action on most gram-negative bacilli††, including E. Coli and on most fungi and gram-positive bacteria.
Features and Benefits
Preparation Note
Stock solutions should be sterile filtered and stored at 2-8°C. They are stable at 37°C for 5 days.
Storage and Stability
Other Notes
signalword
Warning
hcodes
Hazard Classifications
Acute Tox. 4 Oral
Storage Class
11 - Combustible Solids
wgk_germany
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
dust mask type N95 (US), Eyeshields, Gloves
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