Skip to Content
MilliporeSigma
All Photos(1)

Key Documents

View All Documentation

M1800900

Methylthioninium chloride

European Pharmacopoeia (EP) Reference Standard

Synonym(s):

Methylene Blue hydrate

Sign Into View Organizational & Contract Pricing
All Photos(1)

About This Item

Empirical Formula (Hill Notation):
C16H18ClN3S · xH2O
CAS Number:
122965-43-9
Molecular Weight:
319.85 (anhydrous basis)
Beilstein/REAXYS Number:
3599847
MDL number:
MFCD00150006
UNSPSC Code:
41116107
PubChem Substance ID:
329817712
NACRES:
NA.24

grade

pharmaceutical primary standard

API family

methylene blue

manufacturer/tradename

EDQM

application(s)

pharmaceutical (small molecule)

format

neat

storage temp.

2-8°C

SMILES string

O.[Cl-].CN(C)c1ccc2N=C3C=C\C(C=C3Sc2c1)=[N+](/C)C

InChI

1S/C16H18N3S.ClH.H2O/c1-18(2)11-5-7-13-15(9-11)20-16-10-12(19(3)4)6-8-14(16)17-13;;/h5-10H,1-4H3;1H;1H2/q+1;;/p-1

InChI key

WQVSELLRAGBDLX-UHFFFAOYSA-M

Looking for similar products? Visit Product Comparison Guide

General description

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia.For further information and support please go to the website of the issuing Pharmacopoeia.

Application

Methylthioninium chloride EP Reference standard, intended for use in laboratory tests only as specifically prescribed in the European Pharmacopoeia.

Packaging

The product is delivered as supplied by the issuing Pharmacopoeia. For the current unit quantity, please visit the EDQM reference substance catalogue.

Other Notes

Sales restrictions may apply.

Related product

Product No.
Description
Pricing

pictograms

Exclamation mark
GHS07

signalword

Warning

hcodes

H302

Hazard Classifications

Acute Tox. 4 Oral

Storage Class

11 - Combustible Solids

wgk_germany

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

Choose from one of the most recent versions:

Certificates of Analysis (COA)

Lot/Batch Number

Sorry, we don't have COAs for this product available online at this time.

If you need assistance, please contact Customer Support.

Already Own This Product?

Find documentation for the products that you have recently purchased in the Document Library.

Visit the Document Library

Methaemoglobinaemia.
Bradberry S.
Medicine, 35(10), 552-553 (2007)
Pavel Rodriguez et al.
Brain imaging and behavior, 11(3), 640-648 (2016-03-11)
Methylene blue USP (MB) is a FDA-grandfathered drug used in clinics to treat methemoglobinemia, carbon monoxide poisoning and cyanide poisoning that has been shown to increase fMRI evoked blood oxygenation level dependent (BOLD) response in rodents. Low dose MB also
Methylthioninium chloride reverses cognitive deficits induced by scopolamine: comparison with rivastigmine.
Deiana S, et al.
Psychopharmacology (Psychopharmacologia), 202(1-3), 53-53 (2009)
Asfandyar Khan et al.
Nanomaterials (Basel, Switzerland), 11(1) (2021-01-21)
Heterogeneous photo-Fenton systems offer efficient solutions for the treatment of wastewaters in the textile industry. This study investigated the fabrication and structural characterization of novel peculiar-shaped CuIIO, FeIII
Pavel Rodriguez et al.
Radiology, 281(2), 516-526 (2016-10-19)
Purpose To investigate the sustained-attention and memory-enhancing neural correlates of the oral administration of methylene blue in the healthy human brain. Materials and Methods The institutional review board approved this prospective, HIPAA-compliant, randomized, double-blinded, placebo-controlled clinical trial, and all patients
View All Related Papers

Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.

Contact Technical Service