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30-2270

Sigma-Aldrich

Thymol Blue

JIS special grade

Synonym(s):

Thymolsulfonphthalein

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About This Item

Empirical Formula (Hill Notation):
C27H30O5S
CAS Number:
76-61-9
Molecular Weight:
466.59
Beilstein/REAXYS Number:
368036
MDL number:
MFCD00005869
UNSPSC Code:
12171502
PubChem Substance ID:
329753350

grade

JIS special grade

form

solid

availability

available only in Japan

visual transition interval

1.2-2.8, red to yellow
8.0-9.2, yellow to blue

mp

221-224 °C (dec.) (lit.)

SMILES string

CC(C)c1cc(c(C)cc1O)C2(OS(=O)(=O)c3ccccc23)c4cc(C(C)C)c(O)cc4C

InChI

1S/C27H30O5S/c1-15(2)19-13-22(17(5)11-24(19)28)27(21-9-7-8-10-26(21)33(30,31)32-27)23-14-20(16(3)4)25(29)12-18(23)6/h7-16,28-29H,1-6H3

InChI key

PRZSXZWFJHEZBJ-UHFFFAOYSA-N

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Storage Class

11 - Combustible Solids

wgk_germany

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

Certificates of Analysis (COA)

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Yong-Doo Park et al.
Journal of protein chemistry, 22(5), 473-480 (2003-12-24)
Sensitive assay methods for tyrosinase are essential not only for the understanding the process of pigment production but also for the development of effective inhibitors of tyrosinase. To develop an efficient assay method, we applied thymol blue to reaction mixtures.
J G Eley et al.
The Journal of pharmacy and pharmacology, 41(12), 858-860 (1989-12-01)
The interaction of low density lipoprotein (LDL) with two model dyes in the presence or absence of non-ionic surfactants has been studied. The water soluble dye, thymol blue, only weakly interacts with LDL to cause slight increases in particle size
Naoki Hirayama et al.
Analytical sciences : the international journal of the Japan Society for Analytical Chemistry, 28(6), 541-543 (2012-06-26)
The use of a hydrophilic ionic liquid (IL), 1-butyl-3-methylimidazolium chloride (C(4)mimCl), as a salting-out phase separation agent to a water-tetrahydrofuran homogeneous system was studied for possible applications to novel aqueous biphasic extraction separation. The IL showed a salting-out phase-separation ability.
N Gayathri et al.
Journal of AOAC International, 84(4), 1065-1069 (2001-08-15)
A simple and sensitive spectrophotometric method was developed for the determination of trace amounts of sulfur dioxide. The method is based on the reaction of SO2 with a known excess of ICI as the oxidant. The unreacted ICI iodinates thymol
Shangjie Xu et al.
Macromolecular bioscience, 7(8), 968-974 (2007-08-01)
A simple general synthetic concept to build dendritic core-shell architectures with pH-labile linkers based on hyperbranched PEI cores and biocompatible PEG shells is presented. Using these dendritic core-shell architectures as nanocarriers, the encapsulation and transport of polar dyes of different
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