MAB4163

Anti-MDR1 Antibody, extracellular human specific Pgp, clone MC57

clone MC57, Chemicon^®, from mouse

• Synonym(s): P-glycoprotein, CD243, p170, Pgp
• UNSPSC Code: 12352203
• eCl@ss: 32160702
• NACRES: NA.42

Properties

• biological source: mouse
• Quality Level: 300
• antibody form: purified immunoglobulin
• antibody product type: primary antibodies
• clone: MC57, monoclonal
• species reactivity: human
• manufacturer/tradename: Chemicon^®
• technique(s): flow cytometry: suitable; immunohistochemistry (formalin-fixed, paraffin-embedded sections): suitable
• isotype: IgG2aκ
• NCBI accession no.: NM_000927.3
• UniProt accession no.: P08183
• shipped in: wet ice
• Gene Information: human ... ABCB1(5243)

Description

Specificity

MDR-1 clone MC57 recgonizes the inactivated form of Pgp and recognizes the conformational epitope in Immunohistochemistry on paraffin sections.

Immunogen

Epitope: extracellular human specific Pgp

Living intact human multidrug-resistant cells

Application

Anti-MDR1 Antibody, extracellular human specific Pgp, clone MC57 detects level of MDR1 & has been published & validated for use in FC, IH, IH(P).

Flow Cytometry

Immunohistochemistry

Immunohistochemistry on paraffin sections

Functional Experiments

Optimal working dilutions must be determined by end user.

Research Category
Metabolism

Research Sub Category
Toxicology & Drug Resistance

Physical form

Format: Purified

Purified immunoglobulin from Protein A Sepharose chromatography. Liquid in 0.02M PB, pH 7.6, 0.25M NaCl containing 0.1% sodium azide.

Storage and Stability

Maintain at 2-8°C in undiluted aliquots for up to 6 months.

Other Notes

Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.

Legal Information

CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Safety Information

• Storage Class: 10 - Combustible liquids
• wgk_germany: WGK 2
• flash_point_f: Not applicable
• flash_point_c: Not applicable