MAB3502-I

Anti-Angiotensin Converting Enzyme Antibody, clone 2E2

culture supernatant, clone 2E2, from mouse

• Synonym(s): Angiotensin-converting enzyme, ACE, Dipeptidyl carboxypeptidase I, Kininase II, CD143
• UNSPSC Code: 12352203
• eCl@ss: 32160702
• NACRES: NA.41

Properties

• biological source: mouse
• Quality Level: 100
• antibody form: culture supernatant
• antibody product type: primary antibodies
• clone: 2E2, monoclonal
• species reactivity: rat
• species reactivity (predicted by homology): human (immunogen homology)
• technique(s): western blot: suitable
• isotype: IgG1
• NCBI accession no.: NP_000780
• UniProt accession no.: P12821
• shipped in: wet ice
• target post-translational modification: unmodified
• Gene Information: human ... ACE(1636)

Description

General description

Angiotensin-converting enzyme (ACE) is a zinc-metallopeptidase belonging to the peptidase M2 family. It catalyzes the conversion of angiotensin I to angiotensin II and the degradation of bradykinin, which increases the vasoconstrictive effects of angiotensin. The Angiotensin-converting enzyme plays an important role in maintaining cardiac function and vascular tone. It is highly expressed in the heart, lung, kidney, gastrointestinal system, and prostate. Defects in the Angiotensin-converting may contribute cardiac disease; and renal tubular dysgenesis, a condition characterized by persistent fetal anuria and perinatal death.

Immunogen

Human Angiotensin Converting Enzyme.

Application

Anti-Angiotensin Converting Enzyme Antibody, clone 2E2.

Quality

Evaluated by Western Blot in rat Angiotensin Converting Enzyme.

Western Blot Analysis: A 1:2,000 dilution of this antibody detected rat Angiotensin Converting Enzyme in WB.

Target description

~180 kDa observed. The calculated molecular weight is 150 kDa; however, this protein is known to be glycolsylated.

Linkage

Replaces: MAB3502

Physical form

Mouse monoclonal IgG1 cultured supernatant without preservatives.

Analysis Note

Control
Rat Angiotensin Converting Enzyme

Safety Information

• Storage Class: 10 - Combustible liquids
• wgk_germany: WGK 1
• flash_point_f: Not applicable
• flash_point_c: Not applicable