CBL561
Anti-CD24 Antibody, clone SN3
clone SN3, Chemicon®, from mouse
Synonym(s):
Heat Stable Antigen, HAS
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About This Item
UNSPSC Code:
12352203
eCl@ss:
32160702
NACRES:
NA.41
Recommended Products
biological source
mouse
Quality Level
antibody form
affinity purified immunoglobulin
antibody product type
primary antibodies
clone
SN3, monoclonal
species reactivity
human
manufacturer/tradename
Chemicon®
technique(s)
flow cytometry: suitable
immunohistochemistry: suitable
immunoprecipitation (IP): suitable
isotype
IgG1
NCBI accession no.
UniProt accession no.
shipped in
dry ice
target post-translational modification
unmodified
Gene Information
human ... CD24(100133941)
Specificity
The antibody reacts with the CD24 antigen a heavily glycosylated molecule that migrates as a broad band of 35-45 kDa on both reducing and non-reducing SDS gel electrophoresis. CD24 is attached to the cell membrane via a glycosyl phosphatidylinositol (GPI) anchor and is expressed at multiple stages of B cell development, beginning with the bone marrow CD34 positive pro-B cell compartment and continuing through mature surface IgM positive/IgD positive B cells. CD24 is also expressed on the vast majority of B-lineage acute lymphoblastic leukaemias, B cell chronic lymphocytic leukaemias and B cell non-Hodgkin′s lymphoma. In the normal spleen, mantle zone lymphocytes are CD24 strongly positive, but germinal center cells are CD24 negative or CD24 weakly positive.
Immunogen
Glycoproteins purified from human NALM-1 cell line.
Application
Anti-CD24 Antibody, clone SN3 detects level of CD24 & has been published & validated for use in FC, IP, IH.
Immunocytochemistry on frozen tissue sections.
Flow Cytometry: 1:50 - 1:100 per 10e6 cells in 100 μL final volume.
Optimal working dilutions must be determined by the end user.
Flow Cytometry: 1:50 - 1:100 per 10e6 cells in 100 μL final volume.
Optimal working dilutions must be determined by the end user.
Research Category
Inflammation & Immunology
Inflammation & Immunology
Research Sub Category
Immunoglobulins & Immunology
Immunoglobulins & Immunology
Physical form
Affinity purified immunoglobulin by Protein G chromatography. Liquid in 1 mL of PBS, pH 7.4 containing no preservatives.
Format: Purified
Storage and Stability
Maintain at -20°C for up to 12 months from date of receipt in undiluted aliquots.
Other Notes
Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.
Legal Information
CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany
Disclaimer
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
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Storage Class
12 - Non Combustible Liquids
wgk_germany
WGK 2
flash_point_f
Not applicable
flash_point_c
Not applicable
Certificates of Analysis (COA)
Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.
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Chronic lymphocytic leukemia progenitor cells carry the antigens T65, BA-1, and Ia.
Perri, R T, et al.
Blood, 61, 871-875 (1983)
Follicular mantle zone cell subpopulations detected by monoclonal antibody SN3.
Barcos, M, et al.
Hematological Oncology, 4, 251-259 null
Clinical usefulness of monoclonal-antibody phenotyping in childhood acute lymphoblastic leukemia.
Kersey, J, et al.
Lancet, 2, 1419-1423 (1982)
New monoclonal antibodies SN3, SN3a, and SN3b directed to sialic acid of glycoprotein on human non-T leukemia cells.
Fukukawa, T, et al.
Experimental Hematology, 14, 850-855 (1986)
The human fetal omentum: a site of B cell generation.
Solvason, N and Kearney, J F
The Journal of Experimental Medicine, 175, 397-404 (1992)
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