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Key Documents

AG714

Sigma-Aldrich

Human IgG, Fc Fragment

Synonym(s):

IgG Fc Fragment

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About This Item

UNSPSC Code:
12352203
eCl@ss:
32160702
NACRES:
NA.41

biological source

human

Quality Level

antibody form

purified immunoglobulin

manufacturer/tradename

Chemicon®

shipped in

wet ice

target post-translational modification

unmodified

General description

Product Source: Human serum. Tested by an FDA approved test method and found negative for HIV antibody, Hepatitis B Surface Antigen, antibody to Hepatitis C and syphilis.

Application

Research Category
Controls

Physical form

Format: Purified
Sterile liquid in 0.01 M Sodium Phosphate, 0.25 M NaCl, pH 7.6. No preservatives have been added.

Storage and Stability

Store under sterile conditions at +2-8°C for up to one year. Dilute only as needed for a single day′s use.

Analysis Note

Single precipitin line by immunoelectrophoresis at 20 mg/mL against Goat anti-Human whole serum. No cross-reactivity against Goat anti-Human IgG F(ab′)2 fragment, IgM, Fc(5μ) or IgA, alpha-chain specific. Purified by column chromatography.

Legal Information

CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany

Disclaimer

RESEARCH USE ONLY. This product is regulated in France when intended to be used for scientific purposes, including for import and export activities (Article L 1211-1 paragraph 2 of the Public Health Code). The purchaser (i.e. enduser) is required to obtain an import authorization from the France Ministry of Research referred in the Article L1245-5-1 II. of Public Health Code. By ordering this product, you are confirming that you have obtained the proper import authorization.
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Storage Class

12 - Non Combustible Liquids

wgk_germany

WGK 2

flash_point_f

Not applicable

flash_point_c

Not applicable


Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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Iftiin Hassan Mohamed et al.
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The immunoinhibitory receptor Siglec-8 on the surface of human eosinophils and mast cells binds to sialic acid-containing ligands in the local milieu, resulting in eosinophil apoptosis, inhibition of mast cell degranulation, and suppression of inflammation. Siglec-8 ligands were found on
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The Eph-ephrin system, including the EphA2 receptor and the ephrinA1 ligand, plays a critical role in tumor and vascular functions during carcinogenesis. We previously identified (3α,5β)-3-hydroxycholan-24-oic acid (lithocholic acid) as an Eph-ephrin antagonist that is able to inhibit EphA2 receptor

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