8.51088
TOTU
Novabiochem®
Synonym(s):
TOTU, O-[(Ethoxycarbonyl)cyanomethylenamino]-N,N,NÆ,NÆ-tetramethyluronium tetrafluoroborate
About This Item
Recommended Products
Quality Level
product line
Novabiochem®
assay
≥99.0% (HPLC)
form
powder
potency
500-650 mg/kg LD50, oral (Rat)
reaction suitability
reaction type: Coupling Reactions
manufacturer/tradename
Novabiochem®
mp
142-148 °C
application(s)
peptide synthesis
storage temp.
2-8°C
InChI
1S/C10H17N4O3.BF4/c1-6-16-9(15)8(7-11)12-17-10(13(2)3)14(4)5;2-1(3,4)5/h6H2,1-5H3;/q+1;-1
InChI key
FPQVGDGSRVMNMR-UHFFFAOYSA-N
Related Categories
General description
Associated Protocols and Technical Articles
Guide to Selection of Coupling Reagents
Literature references
[1] G. Breipohl & W. Koenig, US patent 5166394.
Analysis Note
Appearance of substance (visual): powder
Identity (IR): conforms
Assay (HPLC, area%): ≥ 99.0 % (a/a)
Solubility (1 mmole in 2 ml DMF): clear soluble
Legal Information
signalword
Danger
Hazard Classifications
Acute Tox. 4 Oral - Eye Dam. 1 - Skin Sens. 1A - STOT SE 3
target_organs
Respiratory system
Storage Class
11 - Combustible Solids
wgk_germany
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
Certificates of Analysis (COA)
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Articles
Novabiochem® offers a large number of coupling reagents for in situ activation. In situ activating reagents are easy to use, fast reacting – even with sterically hindered amino acids, and their use is generally free of side reactions.
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