8.01661

γ-Butyrolactone

Technipur^®, for synthesis

• Synonym(s): γ-Hydroxybutyric acid lactone, 4-Hydroxybutyric acid lactone, GBL
• Empirical Formula (Hill Notation): C₄H₆O₂
• CAS Number: 96-48-0
• Molecular Weight: 86.09
• Beilstein/REAXYS Number: 105248
• MDL number: MFCD00005386
• UNSPSC Code: 12352100
• NACRES: NA.21

Properties

• grade: for synthesis
• Quality Level: 200
• vapor density: 3 (vs air)
• vapor pressure: 0.344 hPa ( 20 °C); 1.5 mmHg ( 20 °C)
• autoignition temp.: 851 °F
• expl. lim.: 16 %
• refractive index: n20/D 1.436 (lit.)
• pH: 4-5 (20 °C, 100 g/L in H₂O)
• bp: 204-205 °C (lit.)
• mp: −45 °C (lit.)
• density: 1.12 g/mL at 25 °C (lit.)
• SMILES string: O=C1CCCO1
• InChI: 1S/C4H6O2/c5-4-2-1-3-6-4/h1-3H2
• InChI key: YEJRWHAVMIAJKC-UHFFFAOYSA-N

Description

General description

γ-Butyrolactone is a common food additive used to enhance the aroma of food. It is used as a solvent for lithium-ion batteries since it has a high flashing point, a low freezing point, a high boiling point, a low viscosity, and a high dielectric constant. It is also used as a plasticizer for the solid electrolyte of lithium batteries.

Application

γ-Butyrolactone can be used as:

• A plasticizer to prepare polymer electrolytes containing poly(epichlorohydrin-ethyleneoxide).
• A plasticizer to prepare quasi-solid-state electrolyte applicable in dye-sensitized solar cells.
• An electrolyte in combination with ionic liquids for applications in electrochemical devices.

Biochem/physiol Actions

Precursor of γ-hydroxybutyric acid (GHB). It blocks dopamine release by blocking impulse flow in dopaminergic neurons. Pretreatment with γ-butyrolactone allows detection of autoreceptor-induced dopamine release.

Legal Information

Technipur is a registered trademark of Merck KGaA, Darmstadt, Germany

Safety Information

• pictograms: GHS05,GHS07
• signalword: Danger
• hcodes: H302 - H318 - H336
• pcodes: P261 - P264 - P271 - P280 - P301 + P312 - P305 + P351 + P338
• Hazard Classifications: Acute Tox. 4 Oral - Eye Dam. 1 - STOT SE 3
• target_organs: Central nervous system
• Storage Class: 10 - Combustible liquids
• wgk_germany: WGK 1
• flash_point_f: 208.4 °F - closed cup
• flash_point_c: 98 °C - closed cup