219421

Cathepsin L Inhibitor I

The Cathepsin L Inhibitor I, also referenced under CAS 108005-94-3, controls the biological activity of Cathepsin L. This small molecule/inhibitor is primarily used for Protease Inhibitors applications.

• Synonym(s): Cathepsin L Inhibitor I, Z-FF-FMK
• Empirical Formula (Hill Notation): C₂₇H₂₇FN₂O₄
• CAS Number: 108005-94-3
• Molecular Weight: 462.51
• UNSPSC Code: 12352200
• NACRES: NA.77

Properties

• Quality Level: 100
• form: solid
• manufacturer/tradename: Calbiochem^®
• storage condition: OK to freeze; desiccated
• color: white
• solubility: DMSO: 20 mM
• shipped in: ambient
• storage temp.: −20°C

Description

General description

A potent, cell-permeable and irreversible inhibitor of cathepsin L.

A potent, cell-permeable, and irreversible inhibitor of Cathepsin L (Cat. No. 219402).

Biochem/physiol Actions

Cell permeable: yes

Primary Target
cathepsin L

Product does not compete with ATP.

Reversible: no

Warning

Toxicity: Standard Handling (A)

Sequence

Z-Phe-Phe-CH₂F

Reconstitution

Following reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.

Analysis Note

single spot by TLC

Other Notes

Ravanko, K., et al. 2004. Cancer Res.64, 8831.
Esser, R.E., et al. 1994. Arthritis Rheum. 37, 236.
Shaw, E., et al. 1993. FEBS Lett.334, 340.

Legal Information

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

Safety Information

• Storage Class: 11 - Combustible Solids
• wgk_germany: WGK 1
• flash_point_f: Not applicable
• flash_point_c: Not applicable