1.10841

p-Toluidine

GR for analysis

• Synonym(s): 4-Aminotoluene, 4-Methylaniline, 4-Aminotoluene, 4-Methylaniline
• Linear Formula: CH₃C₆H₄NH₂
• CAS Number: 106-49-0
• Molecular Weight: 107.15
• Beilstein/REAXYS Number: 471281
• MDL number: MFCD00007906
• UNSPSC Code: 12352116
• EC Index Number: 203-403-1
• NACRES: NA.21

Properties

• vapor density: 3.9 (vs air)
• Quality Level: 100
• assay: ≥99.0% (GC)
• form: solid
• autoignition temp.: 899 °F
• potency: 336 mg/kg LD₅₀, oral (Rat); 890 mg/kg LD₅₀, skin (Rabbit)
• expl. lim.: 6.6 %
• bp: 200 °C/1,013 hPa; 200 °C (lit.)
• mp: 41-46 °C (lit.)
• transition temp: flash point 87 °C
• density: 0.973 g/mL at 25 °C (lit.)
• storage temp.: 2-30°C
• SMILES string: Cc1ccc(N)cc1
• InChI: 1S/C7H9N/c1-6-2-4-7(8)5-3-6/h2-5H,8H2,1H3
• InChI key: RZXMPPFPUUCRFN-UHFFFAOYSA-N

Description

Application

• Preparation of Porous Organic Cage and its use as Chiral Stationary Phase for Capillary Electrochromatography: Research on p-toluidine-derived chiral stationary phases for enhanced electrochromatographic separations, emphasizing its utility in chiral drug analysis and purification (Zheng et al., 2023).
• Comprehensive N- and O-Glycoproteomic Analysis of Multiple Chinese Hamster Ovary Host Cell Lines: Application of p-toluidine in the detailed glycoproteomic analysis, demonstrating its role in enhancing detection and analysis techniques in cellular biology (Wang et al., 2022).
• Degradation of Isoproturon in vitro by a Mix of Bacterial Strains Isolated from Arable Soil: Utilizing p-toluidine-related methodologies for environmental monitoring and degradation studies, showcasing its importance in agricultural chemistry (Duc, 2022).

Analysis Note

Purity (GC): ≥ 99
Identity (IR-spectrum): passes test
Melting range: 43 - 46
o-Toluidine (GC): ≤ 0.1 %
m-Toluidine (GC): ≤ 0.2 %
Performance test (for the determination of hydroxy methylfurfurale): passes test

Safety Information

• pictograms: GHS06,GHS08,GHS09
• signalword: Danger
• hcodes: H301 + H311 + H331 - H317 - H319 - H351 - H410
• pcodes: P273 - P280 - P301 + P310 - P302 + P352 + P312 - P304 + P340 + P311 - P305 + P351 + P338
• Hazard Classifications: Acute Tox. 3 Dermal - Acute Tox. 3 Inhalation - Acute Tox. 3 Oral - Aquatic Acute 1 - Aquatic Chronic 2 - Carc. 2 - Eye Irrit. 2 - Skin Sens. 1A
• Storage Class: 6.1A - Combustible, acute toxic Cat. 1 and 2 / very toxic hazardous materials
• wgk_germany: WGK 3
• flash_point_f: 188.6 °F - closed cup
• flash_point_c: 87 °C - closed cup