860536P

Sphinganine-1-Phosphate (d18:0)

Avanti Research^™ - A Croda Brand 860536P, powder

• Synonym(s): D-erythro-sphinganine-1-phosphate
• Empirical Formula (Hill Notation): C₁₈H₄₀NO₅P
• CAS Number: 19794-97-9
• Molecular Weight: 381.49
• UNSPSC Code: 12352211
• NACRES: NA.25

Properties

• form: powder
• packaging: pkg of 1 × 1 mg (860536P-1mg); pkg of 1 × 5 mg (860536P-5mg)
• manufacturer/tradename: Avanti Research^™ - A Croda Brand 860536P
• lipid type: sphingolipids
• shipped in: dry ice
• storage temp.: −20°C
• SMILES string: [H][C@](CCCCCCCCCCCCCCC)(O)[C@]([NH3+])([H])COP([O-])(O)=O
• InChI: 1S/C18H40NO5P/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-18(20)17(19)16-24-25(21,22)23/h17-18,20H,2-16,19H2,1H3,(H2,21,22,23)/t17-,18+/m0/s1
• InChI key: YHEDRJPUIRMZMP-ZWKOTPCHSA-N

Description

General description

Sphinganine-1-Phosphate (SA1P) is a bioactive lipid present in mammals. It is produced from the sphingoid base, sphinganine in the presence of sphingosine kinase (SPHK).

Application

Sphinganine-1-Phosphate (d18:0) has been used as a reference standard in ultra performance liquid chromatography coupled to a mass spectrometry. It is suitable for use as an internal standard for ultra high performance liquid chromatography for the quantification of blood and muscle sphingolipid. Sphinganine-1-phosphate (d18:0) is also suitable for use as standard in liquid chromatography tandem mass spectrometry.

Biochem/physiol Actions

Sphinganine-1-Phosphate (SA1P) is an important marker for cancer and immune system disorders studies. It elicits protective functionality in hepatic ischemia. Elevated levels of SA1P is observed in hepatocellular carcinoma.

Packaging

5 mL Amber Glass Screw Cap Vial (860536P-1mg)

5 mL Amber Glass Screw Cap Vial (860536P-5mg)

Legal Information

Avanti Research is a trademark of Avanti Polar Lipids, LLC

Safety Information

• Storage Class: 11 - Combustible Solids
• wgk_germany: WGK 3
• flash_point_f: Not applicable
• flash_point_c: Not applicable