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type
for DNA synthesis
Quality Level
product line
Proligo Reagents
form
liquid
storage condition
dry at room temperature
impurities
≤200 ppm water content (Karl Fischer)
color
clear
suitability
conforms to structure (GC, Formulation)
compatibility
configured for ABI
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General description
Cap B solution contains tetrahydrofuran (THF), pyridine, and N-methylimidazole (NMI). It is mixed in situ with Cap A solution during the capping (acetylation) reaction. Pyridine is applied as a mild base while NMI provides a powerful acylation catalyst.
Preparation Note
Tetrahydrofurane / N-Methylimidazole 84/16 (v/v)
Other Notes
Cap B solution, containing tetrahydrofuran (THF) and N-methylimidazole (NMI), is mixed in situ with Cap A solution during the capping (acetylation) reaction. Lutidine is applied as a mild base while NMI provides a powerful acylation catalyst.
signalword
Danger
Hazard Classifications
Acute Tox. 4 Oral - Carc. 2 - Eye Dam. 1 - Flam. Liq. 2 - Repr. 2 - Skin Corr. 1B - STOT SE 3
target_organs
Central nervous system, Respiratory system
supp_hazards
Storage Class
3 - Flammable liquids
wgk_germany
WGK 2
flash_point_f
6.1 °F
flash_point_c
-14.4 °C
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