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791369

Sigma-Aldrich

Tang-Yu Auxiliary

97%

Synonym(s):

2-(2-Cyanophenoxy)-2-fluoroacetic acid

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About This Item

Empirical Formula (Hill Notation):
C9H6FNO3
CAS Number:
Molecular Weight:
195.15
MDL number:
UNSPSC Code:
12352002
PubChem Substance ID:
NACRES:
NA.22

Quality Level

assay

97%

form

solid

reaction suitability

reaction type: C-C Bond Formation
reagent type: catalyst
reagent type: ligand
reaction type: C-H Activation

mp

105-108 °C

functional group

carboxylic acid
fluoro
nitrile

SMILES string

O=C(O)C(F)OC1=C(C#N)C=CC=C1

InChI

1S/C9H6FNO3/c10-8(9(12)13)14-7-4-2-1-3-6(7)5-11/h1-4,8H,(H,12,13)

InChI key

WPPDDNKKUDYVMF-UHFFFAOYSA-N

Application

The Tang-Yu Auxiliary is a recyclable template for highly meta-selective C-H activation of N-methylanilines as reported by Yu and coworkers.

Related product

Product No.
Description
Pricing

Storage Class

11 - Combustible Solids

wgk_germany

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable


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Related Content

The Yu program centers around the discovery of catalytic carbon–carbon and carbon–heteroatom bond forming reactions based on C–H activation. Target transformations are selected to enable 1) the use of simple and abundant starting materials such as aliphatic acids, amines and alcohols, and 2) disconnections that drastically shorten the synthesis of a drug molecule or a major class of biologically active compounds.

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