518786
4-Hydroxy-3-methoxyphenylboronic acid pinacol ester
98%
Synonym(s):
2-Methoxy-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenol, 4-Hydroxy-3-methoxyphenylboronic acid, pinacol cyclic ester
About This Item
Recommended Products
assay
98%
mp
105-109 °C (lit.)
SMILES string
COc1cc(ccc1O)B2OC(C)(C)C(C)(C)O2
InChI
1S/C13H19BO4/c1-12(2)13(3,4)18-14(17-12)9-6-7-10(15)11(8-9)16-5/h6-8,15H,1-5H3
InChI key
WFSJROCEOJANPD-UHFFFAOYSA-N
Application
- In the Suzuki-Miyaura cross-coupling reaction.
- To prepare ethylidenedihydroindolones as potential neoplastic agents.
- To synthesize 5,6-dihydropyrrolo[2,1-b]isoquinoline derivatives, which can be utilized as scaffolds to prepare lamellarin analogs via regioselective bromination and Suzuki cross-coupling reactions.
signalword
Warning
hcodes
Hazard Classifications
Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
target_organs
Respiratory system
Storage Class
11 - Combustible Solids
wgk_germany
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
dust mask type N95 (US), Eyeshields, Gloves
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Articles
The synthesis of biaryl compounds via the Suzuki coupling reaction has become more commonplace now that many arylboronic acids are readily available. We are pleased to offer arylboronic acid pinacol esters4 as part of a growing line of products used in the Suzuki coupling reaction.
The synthesis of biaryl compounds via the Suzuki–Miyaura coupling reaction has become more commonplace now that many arylboronic acids are readily available.
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