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50515

Sigma-Aldrich

Stearyl glycyrrhetinate

≥95.0%

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About This Item

Empirical Formula (Hill Notation):
C48H82O4
CAS Number:
13832-70-7
Molecular Weight:
723.16
Beilstein/REAXYS Number:
7612541
EC Number:
419-580-5
MDL number:
MFCD00674112
UNSPSC Code:
12352108
PubChem Substance ID:
57651256
NACRES:
NA.22

Quality Level

100

assay

≥95.0%

mp

70-77 °C

SMILES string

CCCCCCCCCCCCCCCCCCOC(=O)[C@@]1(C)CC[C@]2(C)CC[C@]3(C)C(=CC(=O)[C@@H]4[C@@]5(C)CC[C@H](O)C(C)(C)[C@@H]5CC[C@@]34C)[C@@H]2C1

InChI

1S/C48H82O4/c1-9-10-11-12-13-14-15-16-17-18-19-20-21-22-23-24-33-52-42(51)45(5)30-29-44(4)31-32-47(7)36(37(44)35-45)34-38(49)41-46(6)27-26-40(50)43(2,3)39(46)25-28-48(41,47)8/h34,37,39-41,50H,9-33,35H2,1-8H3/t37-,39-,40-,41+,44+,45-,46-,47+,48+/m0/s1

InChI key

WNIFXKPDILJURQ-JKPOUOEOSA-N

Related Categories

General description

Stearyl glycyrrhetinate is a stearic acid ester of glycyrrhetinic acid, generally used as a flavoring agent in commercially available cosmetic products.

Application

Stearyl glycyrrhetinate can be used to prepare modified liposomes loaded with norcantharidin and 10-hydroxycamptothecin, which are used as drug delivery systems in cancer therapy.

Storage Class

11 - Combustible Solids

wgk_germany

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)

Certificates of Analysis (COA)

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Final report on the safety assessment of Glycyrrhetinic Acid, Potassium Glycyrrhetinate, Disodium Succinoyl Glycyrrhetinate, Glyceryl Glycyrrhetinate, Glycyrrhetinyl Stearate, Stearyl Glycyrrhetinate, Glycyrrhizic Acid, Ammonium Glycyrrhizate, Dipotassium
International Journal of Toxicology, 26, 79-79 (2007)
Carmelo Puglia et al.
Journal of cosmetic science, 64(5), 341-353 (2013-10-22)
The aim of this study was to assess the ability of some vehicles (emulsion and emulgel), containing hydrogenated lecithin as penetration enhancer, in increasing the percutaneous absorption of the two model compounds dipotassium glycyrrhizinate (DG) and stearyl glycyrrhetinate (SG). Furthermore

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