287067

L-Proline methyl ester hydrochloride

98%, for peptide synthesis

• Synonym(s): (S)-Methyl pyrrolidine-2-carboxylate hydrochloride, L-Pro-OMe HCl
• Empirical Formula (Hill Notation): C₆H₁₁NO₂ · HCl
• CAS Number: 2133-40-6
• Molecular Weight: 165.62
• Beilstein/REAXYS Number: 3596045
• EC Number: 218-363-0
• MDL number: MFCD00012708
• UNSPSC Code: 12352209
• eCl@ss: 32160406
• PubChem Substance ID: 24857264
• NACRES: NA.22

Properties

• product name: L-Proline methyl ester hydrochloride, 98%
• Quality Level: 100
• assay: 98%
• form: solid
• optical activity: [α]20/D −31°, c = 0.5 in H₂O
• reaction suitability: reaction type: solution phase peptide synthesis
• mp: 69-71 °C (lit.)
• application(s): peptide synthesis
• SMILES string: Cl[H].[H][C@]1(CCCN1)C(=O)OC
• InChI: 1S/C6H11NO2.ClH/c1-9-6(8)5-3-2-4-7-5;/h5,7H,2-4H2,1H3;1H/t5-;/m0./s1
• InChI key: HQEIPVHJHZTMDP-JEDNCBNOSA-N

Description

Application

L-Proline methyl ester hydrochloride can be used as:

• A building block in peptide synthesis.
• A catalyst to synthesize 3,4-dihydropyrimidin-2-(1H)-ones via Biginelli condensation reaction with aryl aldehydes, methyl acetoacetate, and urea.
• A reactant to prepare prolylproline.

Safety Information

• Storage Class: 11 - Combustible Solids
• wgk_germany: WGK 3
• flash_point_f: Not applicable
• flash_point_c: Not applicable
• ppe: dust mask type N95 (US), Eyeshields, Gloves