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1125006

USP

Chlorpromazine hydrochloride

United States Pharmacopeia (USP) Reference Standard

Synonim(y):

2-Chloro-10-(3-dimethylaminopropyl)phenothiazine hydrochloride, CPZ, Largactil

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About This Item

Wzór empiryczny (zapis Hilla):
C17H19ClN2S · HCl
Numer CAS:
69-09-0
Masa cząsteczkowa:
355.33
Beilstein:
3779989
Numer MDL:
MFCD00012654
Kod UNSPSC:
41116107
Identyfikator substancji w PubChem:
329749339
NACRES:
NA.24

klasa czystości

pharmaceutical primary standard

rodzina API

chlorpromazine

producent / nazwa handlowa

USP

Zastosowanie

pharmaceutical (small molecule)

Format

neat

temp. przechowywania

2-8°C

ciąg SMILES

Cl[H].CN(C)CCCN1c2ccccc2Sc3ccc(Cl)cc13

InChI

1S/C17H19ClN2S.ClH/c1-19(2)10-5-11-20-14-6-3-4-7-16(14)21-17-9-8-13(18)12-15(17)20;/h3-4,6-9,12H,5,10-11H2,1-2H3;1H

Klucz InChI

FBSMERQALIEGJT-UHFFFAOYSA-N

informacje o genach

human ... DRD2(1813) , DRD3(1814) , DRD4(1815) , HTR2A(3356)

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Opis ogólny

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia.For further information and support please go to the website of the issuing Pharmacopoeia.

Zastosowanie

Chlorpromazine hydrochloride USP reference standard, intended for use in specified quality tests and assays as specified in the USP compendia. Also, for use with USP monographs such as:
  • Chlorpromazine
  • Chlorpromazine Hydrochloride
  • Chlorpromazine Hydrochloride Injection
  • Chlorpromazine Hydrochloride Oral Concentrate
  • Chlorpromazine Hydrochloride Syrup
  • Chlorpromazine Hydrochloride Tablets
Substitute for benzidine, o-dianisidine, and o-tolidine in the determination of microquantities of hemoglobin and peroxidase.

Działania biochem./fizjol.

Chlorpromazine demonstrates cytotoxic and antiproliferative activity against leukemic cells, but does not affect the viability of normal lymphocytes.
Phenothiazine antipsychotic; D2 dopamine receptor antagonist, H1 histamine receptor antagonist; inhibits calmodulin-dependent stimulation of cyclic nucleotide phosphodiesterase and nitric oxide synthase.

Komentarz do analizy

These products are for test and assay use only. They are not meant for administration to humans or animals and cannot be used to diagnose, treat, or cure diseases of any kind.  ​

Inne uwagi

Sales restrictions may apply.
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Piktogramy

Skull and crossbones
GHS06

Hasło ostrzegawcze

Danger

Zwroty wskazujące rodzaj zagrożenia

H301,H330

Zwroty wskazujące środki ostrożności

P260 - P264 - P270 - P271 - P284 - P304 + P340 + P310

Klasyfikacja zagrożeń

Acute Tox. 1 Inhalation - Acute Tox. 3 Oral

Kod klasy składowania

6.1A - Combustible acute toxic Cat. 1 and 2 / very toxic hazardous materials

Klasa zagrożenia wodnego (WGK)

WGK 3

Temperatura zapłonu (°F)

Not applicable

Temperatura zapłonu (°C)

Not applicable

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Certyfikaty analizy (CoA)

Lot/Batch Number

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Sigma-Aldrich

D7693

Dynasore hydrate

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Sigma-Aldrich

A3085

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Sigma-Aldrich

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