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Merck

569224-U

Supelco

Discovery® C18 (5 µm) HPLC Columns

L × I.D. 25 cm × 10 mm, HPLC Column

Synonim(y):

Discovery RP18 HPLC Column

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About This Item

Kod UNSPSC:
41115700
eCl@ss:
32110501
NACRES:
SB.52

product name

Discovery® C18 HPLC Column, 5 μm particle size, L × I.D. 25 cm × 10 mm

Materiały

stainless steel column

Poziom jakości

agency

suitable for USP L1

linia produktu

Discovery®

Właściwości

endcapped

producent / nazwa handlowa

Discovery®

opakowanie

1 ea of

zakres etykietowania

12% Carbon loading

Parametry

≤70 °C temp. range
400 bar pressure (5801 psi)

metody

HPLC: suitable
LC/MS: suitable

dł. × śr. wewn.

25 cm × 10 mm

powierzchnia

300 m2/g

pokrycie powierzchni

3 μmol/m2

zanieczyszczenia

<10 ppm metals

macierz

silica gel, high purity, spherical particle platform
fully porous particle

grupa aktywna macierzy

C18 (octadecyl) phase

wielkość cząstki

5 μm

wielkość porów

180 Å

operating pH range

2-8

Zastosowanie

food and beverages

metoda separacji

reversed phase

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Opis ogólny

Use Discovery® C18 for any method that specifies a C18. The exceptional peak shape, reproducibility, and stability make it the column of choice for all C18 methods from demanding to routine.

Zastosowanie


  • Development and Validation of a Reversed-Phase HPLC Method with UV Detection for the Determination of L-Dopa in Vicia faba L. Broad Beans.: Highlights the application of the Discovery® C18 HPLC Column in developing a method for the accurate quantification of L-Dopa in natural sources, which is essential for studies in neuropharmacology and natural product research (Tesoro et al., 2022).

  • Simultaneous estimation of paclitaxel and erlotinib in plasma by liquid chromatography/(+) electrospray tandem mass spectrometry: application in formulation development and pharmacokinetics.: This study employs the Discovery® C18 HPLC Column to enhance the simultaneous analysis of paclitaxel and erlotinib, critical for cancer therapy research and formulation development (Khuroo et al., 2022).

Cechy i korzyści

  • Excellent reproducibility
  • Exceptional peak shape for basic and acidic analytes
  • Stable, low-bleed LC-MS separations
  • Separation of peptides and small proteins
  • Lower hydrophobicity than many comparable C18 columns, providing faster analysis

Polecane produkty

Discover LiChropur reagents ideal for HPLC or LC-MS analysis

Informacje prawne

Discovery is a registered trademark of Merck KGaA, Darmstadt, Germany
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Dokumenty związane z niedawno zakupionymi produktami zostały zamieszczone w Bibliotece dokumentów.

Odwiedź Bibliotekę dokumentów

T Nagano et al.
Journal of dental research, 88(9), 823-828 (2009-09-22)
Mmp-20 and Klk4 are the two key enamel proteases. Can both enzymes process amelogenin to generate the major cleavage products that accumulate during the secretory stage of amelogenesis? We isolated Mmp-20 and Klk4 from developing pig teeth and used them
Yuan-Qing Xia et al.
Rapid communications in mass spectrometry : RCM, 20(12), 1831-1837 (2006-05-18)
A major challenge in selecting an appropriate stationary phase for diastereomeric separation is that it is difficult to predict which of the commercially available stationary phases could achieve the required liquid chromatographic (LC) separation. This work describes the selection and
T R Shantha Kumar et al.
Journal of pharmaceutical and biomedical analysis, 38(1), 173-179 (2005-05-24)
A simple, precise and accurate isocratic reverse-phase liquid chromatography method with programmed wavelength detection has been validated to quantify DRF-4367 and Phenol red, simultaneously for application in rat in situ single pass intestinal perfusion study to assess intestinal permeability of
Satoru Sonoke et al.
Cancer research, 68(21), 8843-8851 (2008-11-01)
The pharmacokinetics and antitumor activity of pegylated small interfering RNA (siRNA)/cationic liposome complexes were studied after systemic administration to mice. We designed pegylated-lipid carriers for achieving increased plasma concentrations of RNA and hence improved accumulation of RNA in tumors by
Yoshinori Masukawa et al.
Journal of lipid research, 49(7), 1466-1476 (2008-03-25)
Ceramides (CERs) in human stratum corneum (SC) play physicochemical roles in determining barrier and water-holding functions of the skin, and specific species might be closely related to the regulation of keratinization, together with other CER-related lipids. Structures of those diverse

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