T8390

Testosterone 3-(O-carboxymethyl)oxime

• Synonim(y): 17β-Hydroxy-4-androsten-3-one 3-(O-carboxymethyl)oxime, 4-Androsten-17β-ol-3-one 3-(O-carboxymethyl)oxime
• Wzór empiryczny (zapis Hilla): C₂₁H₃₁NO₄
• Numer CAS: 10190-93-9
• Masa cząsteczkowa: 361.48
• Numer MDL: MFCD00056503
• Kod UNSPSC: 51111800
• Identyfikator substancji w PubChem: 24900526
• NACRES: NA.77

Właściwości

• sterylność: non-sterile
• Poziom jakości: 200
• Próba: ≥98.00% (TLC)
• Postać: powder
• drug control: Home Office Schedule 4.2; regulated under CDSA - not available from Sigma-Aldrich Canada
• rozpuszczalność: ethanol: soluble 49-51 mg/mL, clear, colorless to faintly yellow
• Warunki transportu: ambient
• temp. przechowywania: room temp
• ciąg SMILES: [H][C@@]12CCC3=CC(\CC[C@]3(C)[C@@]1([H])CC[C@]4(C)[C@@H](O)CC[C@@]24[H])=N\OCC(O)=O
• InChI: 1S/C21H31NO4/c1-20-9-7-14(22-26-12-19(24)25)11-13(20)3-4-15-16-5-6-18(23)21(16,2)10-8-17(15)20/h11,15-18,23H,3-10,12H2,1-2H3,(H,24,25)/b22-14+/t15-,16-,17-,18-,20-,21-/m0/s1
• Klucz InChI: VDYLVWGBLQNNAW-UVTKPVMCSA-N

Opis

Zastosowanie

Testosterone 3-(O-carboxymethyl)oxime has been used for the hormonal analysis of sexual dimorphism in the electric fish, Apteronotus. This testosterone derivative has also been used for developing environmental biosensors for the detection of testosterone in water samples.

Testosterone 3-(O-carboxymethyl)oxime has been used to prepare horseradish peroxidase (HRP)-labeled testosterone to measure plasma testosterone concentration by enzyme immunoassay.

Działania biochem./fizjol.

Androgens direct the development of male reproductive system and secondary sexual characteristics. Testosterone is an androgen that is secreted by the testis. This hormone is converted to dihydrotestosterone (DHT) by 5α reductase in the target tissues. Both DHT and testosterone require androgen receptor, a ligand-dependent nuclear transcription factor to mediate their biological functions.

Androgens direct the development of the male phenotype during embryogenesis and at puberty. Testosterone is an androgen that is secreted by the testis. This hormone is converted to dihydrotestosterone in the target tissues where it may mediate several biological functions.

Uwaga dotycząca przygotowania

Testosterone 3-(O-carboxymethyl)oxime is soluble in ethanol at 49-51 mg/ml and yields a clear, colorless to faint yellow solution.

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Informacja o środkach bezpieczeństwa

• Piktogramy: GHS08,GHS07
• Hasło ostrzegawcze: Warning
• Zwroty wskazujące rodzaj zagrożenia: H302 + H312 + H332,H351
• Zwroty wskazujące środki ostrożności: P202 - P280 - P301 + P312 - P302 + P352 + P312 - P304 + P340 + P312 - P308 + P313
• Klasyfikacja zagrożeń: Acute Tox. 4 Dermal - Acute Tox. 4 Inhalation - Acute Tox. 4 Oral - Carc. 2
• Kod klasy składowania: 11 - Combustible Solids
• Klasa zagrożenia wodnego (WGK): WGK 3
• Temperatura zapłonu (°F): Not applicable
• Temperatura zapłonu (°C): Not applicable
• Środki ochrony indywidualnej: Eyeshields, Gloves, type P3 (EN 143) respirator cartridges