About This Item
Kod UNSPSC:
12352200
NACRES:
NA.32
Polecane produkty
Formularz
lyophilized powder
Poziom jakości
kolor
white
rozpuszczalność
deionized water: soluble
Warunki transportu
dry ice
temp. przechowywania
−20°C
Powiązane kategorie
Amino Acid Sequence
H-THR-LEU-GLN-PRO-PRO-SER-ALA-LEU-ARG-ARG-ARG-HIS-TYR-HIS-HIS-ALA-LEU-PRO-PRO-SER-ARG-OH
Opis ogólny
TLQP-21 peptide is a derivative of VGF and is expressed at higher levels in the brain.
Działania biochem./fizjol.
TLQP-21 peptide is involved in the central and peripheral nervous system activities such as regulating reproductive and circadian behaviors, feeding, and body weight. It is also involved in regulating neuropathic pain and peripheral adiposity. TLQP-21 plays a role in stimulating the secretion of insulin and prevents apoptosis of pancreatic cells. It also activates the complement C3a receptor-1 (C3aR1) in the brain.
Postać fizyczna
Lyophilized from 0.1% aqueous TFA
Inne uwagi
Lyophilized from 0.1% TFA in H2O
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Kod klasy składowania
11 - Combustible Solids
Klasa zagrożenia wodnego (WGK)
WGK 3
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Dokumenty związane z niedawno zakupionymi produktami zostały zamieszczone w Bibliotece dokumentów.
Wei Zhang et al.
PloS one, 8(11), e79760-e79760 (2013-11-28)
Hyperglycemia causes oxidative stress that could damage vascular endothelial cells, leading to cardiovascular complications. The Vgf gene was identified as a nerve growth factor-responsive gene, and its protein product, VGF, is characterized by the presence of partially cleaved products. One
C Severini et al.
British journal of pharmacology, 157(6), 984-993 (2009-05-27)
Vgf gene expression has been detected in various endocrine and neuronal cells in the gastrointestinal tract. In this study we investigated the pharmacological activity of different VGF-derived peptides. Among these, TLQP-21, corresponding to the 556-576 fragment of the protein was
A Bartolomucci et al.
Proceedings of the National Academy of Sciences of the United States of America, 103(39), 14584-14589 (2006-09-20)
The vgf gene has been identified as an energy homeostasis regulator. Vgf encodes a 617-aa precursor protein that is processed to yield an incompletely characterized panel of neuropeptides. Until now, it was an unproved assumption that VGF-derived peptides could regulate
Huan Liu et al.
Autophagy, 16(12), 2140-2155 (2020-01-22)
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