SRP4757

GDF-3 human

recombinant, expressed in E. coli, ≥98% (SDS-PAGE), ≥98% (HPLC)

• Synonim(y): Growth Diffrentiation Factor-3, Growth/Differentiation Factor-3
• Numer MDL: MFCD07370813
• Kod UNSPSC: 12352202
• NACRES: NA.32

Właściwości

• pochodzenie biologiczne: human
• rekombinowane: expressed in E. coli
• Próba: ≥98% (HPLC); ≥98% (SDS-PAGE)
• Postać: lyophilized
• masa cząsteczkowa: ~13 kDa
• opakowanie: pkg of 20 μg
• warunki przechowywania: avoid repeated freeze/thaw cycles
• zanieczyszczenia: endotoxin, tested
• numer dostępu NCBI: Q9NR23
• numer dostępu UniProt: Q9NR23
• Warunki transportu: wet ice
• temp. przechowywania: −20°C
• informacje o genach: human ... GDF3(9573)

Opis

Opis ogólny

GDF-3 is a member of the TGF-β superfamily of growth and differentiation factors, and is highly homologous to GDF-9. Unlike most TGF-β family members, GDF-3 and GDF-9 are not disulfide-linked dimers. GDF-3 is expressed in adult bone marrow, spleen, thymus, and adipose tissue. The expression of GDF-3 is upregulated in high-fat-fed wild-type FABP4/aP2 null mice and was associated with obesity, but not with the related hyperglycemia/hyperinsulinemia which characterizes Type-2 diabetes. Recombinant human GDF-3 contains 114 amino acids polypeptide chains

Postać fizyczna

Sterile filtered and lyophilized with no additives.

Rekonstytucja

Centrifuge the vial prior to opening. Avoid freeze-thaw cycles.

Reconstitute in water to a concentration of 0.1-1.0 mg/mL. The solution can then be diluted into other aqueous buffers.

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