SRP3279
BMP-5 human
recombinant, expressed in CHO cells, ≥95% (SDS-PAGE), ≥95% (HPLC)
Synonim(y):
none
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About This Item
Polecane produkty
pochodzenie biologiczne
human
rekombinowane
expressed in CHO cells
Próba
≥95% (HPLC)
≥95% (SDS-PAGE)
Postać
lyophilized
siła działania
0.5-1.0 μg/mL ED50
masa cząsteczkowa
31.2 kDa
opakowanie
pkg of 10 μg
zanieczyszczenia
<0.1 EU/μg endotoxin, tested
kolor
white to off-white
numer dostępu UniProt
Warunki transportu
wet ice
temp. przechowywania
−20°C
informacje o genach
human ... BMP5(653)
Opis ogólny
As implied by their name, BMPs initiate, promote, and regulate the development, growth and remodeling of bone and cartilage. In addition to this role, BMPs are also involved in prenatal development and postnatal growth, remodeling and maintenance of a variety of other tissues and organs.
Działania biochem./fizjol.
TGF-β family members are key modulators of cell proliferation, differentiation, matrix synthesis, and apoptosis. BMP-5 is expressed in the nervous system, lung and liver. It is a known regulator for dendritic growth in sympathetic neurons. BMP-5 is a 454 amino acid precursor protein that is cleaved to release the biologically active C-terminal mature protein. Recombinant human BMP-5 is a 15.6 kDa homodimeric disulfide-linked protein consisting of two identical 138 amino acid chains.
Postać fizyczna
Lyophilized with no additives.
Rekonstytucja
Centrifuge the vial prior to opening. Reconstitute in water to a concentration of 0.1-1.0 mg/mL. Do not vortex. This solution can be stored at 2-8°C for up to 1 week. For extended storage, it is recommended to further dilute in a buffer containing a carrier protein (example 0.1% BSA) and store in working aliquots at -20°C to -80°C.
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Kod klasy składowania
10 - Combustible liquids
Klasa zagrożenia wodnego (WGK)
WGK 3
Temperatura zapłonu (°F)
Not applicable
Temperatura zapłonu (°C)
Not applicable
Certyfikaty analizy (CoA)
Poszukaj Certyfikaty analizy (CoA), wpisując numer partii/serii produktów. Numery serii i partii można znaleźć na etykiecie produktu po słowach „seria” lub „partia”.
Masz już ten produkt?
Dokumenty związane z niedawno zakupionymi produktami zostały zamieszczone w Bibliotece dokumentów.
Growth factors (Chur, Switzerland), 22(4), 233-241 (2004-12-29)
Bone morphogenetic proteins (BMPs) are multi-functional growth factors that belong to the transforming growth factor beta (TGFbeta) superfamily. The roles of BMPs in embryonic development and cellular functions in postnatal and adult animals have been extensively studied in recent years.
Theriogenology, 84(4), 589-599 (2015-05-28)
Previous studies have reported that bone morphogenetic protein 5 (BMP5) is differentially expressed in the isthmus of bovine oviducts and it is present in the oviductal fluid. However, the specific action of this factor is unknown. To evaluate whether BMP5
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