SAB5700330

Anti-Phospho-STAT1-S727 antibody produced in rabbit

• Synonim(y): CANDF7, IMD31A, IMD31B, IMD31C, ISGF-3, STAT1, STAT1 alpha, STAT91
• Kod UNSPSC: 12352203
• NACRES: NA.41

Właściwości

• pochodzenie biologiczne: rabbit
• Poziom jakości: 100
• forma przeciwciała: affinity isolated antibody
• rodzaj przeciwciała: primary antibodies
• klon: polyclonal
• Postać: buffered aqueous solution
• masa cząsteczkowa: 83; 87
• reaktywność gatunkowa: mouse, human, rat
• stężenie: 1.31 mg/ml
• metody: immunohistochemistry: 1:50-1:100; immunoprecipitation (IP): 1:50-1:100; western blot: 1:500-1:2000
• numer dostępu UniProt: P42224
• Warunki transportu: wet ice
• temp. przechowywania: −20°C
• docelowa modyfikacja potranslacyjna: phosphorylation (pSer727)
• informacje o genach: human ... STAT1(6772)

Opis

Opis ogólny

The protein encoded by this gene is a member of the STAT protein family. In response to cytokines and growth factors, STAT family members are phosphorylated by the receptor associated kinases, and then form homo- or heterodimers that translocate to the cell nucleus where they act as transcription activators. This protein can be activated by various ligands including interferon-alpha, interferon-gamma, EGF, PDGF and IL6. This protein mediates the expression of a variety of genes, which is thought to be important for cell viability in response to different cell stimuli and pathogens. Two alternatively spliced transcript variants encoding distinct isoforms have been described.

Immunogen

A synthetic phosphorylated peptide around S727 of human STAT1 (NP_009330.1).

Postać fizyczna

PBS with 0.02% sodium azide,50% glycerol,pH7.3.

Przechowywanie i stabilność

Store at -20℃. Avoid freeze / thaw cycles.

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Informacja o środkach bezpieczeństwa

• Kod klasy składowania: 12 - Non Combustible Liquids
• Klasa zagrożenia wodnego (WGK): WGK 1
• Temperatura zapłonu (°F): Not applicable
• Temperatura zapłonu (°C): Not applicable