SAB5202071

Monoclonal Anti-beta 4 Spectrin-Horseradish Peroxidase antibody produced in mouse

clone S393-2, affinity isolated antibody, buffered aqueous solution

• Synonim(y): Anti-SPTBN4
• Kod UNSPSC: 12352203
• NACRES: NA.45

Właściwości

• pochodzenie biologiczne: mouse
• białko sprzężone: peroxidase conjugate
• forma przeciwciała: affinity isolated antibody
• rodzaj przeciwciała: primary antibodies
• klon: S393-2; monoclonal
• opis: clone S393-2, purified immunoglobulin, buffered aqueous solution; target molecular weight: 200 kDa
• Postać: buffered aqueous solution
• reaktywność gatunkowa: human (Tested), rat (Predicted), African green monkey (Tested), mouse (Predicted)
• opakowanie: pkg of 100 μg
• warunki przechowywania: avoid repeated freeze/thaw cycles; protect from light
• stężenie: 1.0 mg/mL
• metody: immunofluorescence: 1:100; western blot: 1:1000
• izotyp: IgG1
• numer dostępu UniProt: Q9H254
• Warunki transportu: wet ice
• temp. przechowywania: −20°C
• docelowa modyfikacja potranslacyjna: unmodified
• informacje o genach: human ... SPTBN4(57731)

Opis

Immunogen

Immunogen Description: Fusion protein amino acids 1621-1832 (C-terminal repeats 14 to 15) of human Beta4-spectrin

Immunogen Region: C-terminal

Immunogen Species: Human

Immunogen type: Fusion protein

Zastosowanie

Western blotting
Dilution 1:1000
Tissue/Cell Type Used: monkey COS-Beta-4-Spectrin-His

Immunofluorescence
Dilution 1:100
Tissue/Cell Type Used: SK-N-BE

Postać fizyczna

50% glycerol, 0.1% sodium azide

PBS pH 7.4

Uwaga dotycząca przygotowania

Derived from animal serum

Przechowywanie i stabilność

Protect from light; avoid repeated freeze-thaw cycles. Store at -20 °C long-term, 2-8 °C short-term.

Inne uwagi

Additional Product Details:
Does not cross react with other Beta-spectrins
Lot Expiration/Retest Date: Expires 1 year from purchase

Target/Gene Description: Spectrin is the major constituent of the cytoskeletal network underlying the erthrocyte plasma membrane and determines cell shape, arrangement of transmembrane proteins and organization of organelles. It is expressed at very low levels in many tissues, with the strongest expression in the cerebellum, spinal cord, stomach, pituitary gland, liver, pancreas, salivary gland, kidney, bladder and heart . Spectrin beta 4 is a non-erythrocyte member, and is expressed in the brain and pancreatic islets and localisted to the nuclear matrix, cytoplasmic vesicles and PML nuclear bodies. Beta4 spectrins are also essential for membrane stability and the molecular organization of the nodes of Ranvier .
Purification method: Protein G purified
Product type: Primary antibody
Antibody structure: Whole Antibody
Protein ID: NP_066022.2

Oświadczenie o zrzeczeniu się odpowiedzialności

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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Informacja o środkach bezpieczeństwa

• Kod klasy składowania: 10 - Combustible liquids
• Klasa zagrożenia wodnego (WGK): WGK 2
• Temperatura zapłonu (°F): Not applicable
• Temperatura zapłonu (°C): Not applicable