SAB4702061

Monoclonal Anti-CD10 APC-Cyanine7 produced in mouse

• Synonim(y): Atriopeptidase, CALLA, Enkephalinase, MME, Neprilysin, Neutral endopeptidase
• Kod UNSPSC: 12352203

Właściwości

• białko sprzężone: APC-Cy7 conjugate
• Poziom jakości: 100
• rodzaj przeciwciała: primary antibodies
• klon: MEM-78, monoclonal
• Postać: buffered aqueous solution
• reaktywność gatunkowa: human
• metody: flow cytometry: suitable
• izotyp: IgG1
• numer dostępu UniProt: P08473
• temp. przechowywania: 2-8°C
• docelowa modyfikacja potranslacyjna: unmodified
• informacje o genach: human ... MME(4311)

Opis

Opis ogólny

CD10 (neutral endopeptidase – NEP, common acute lymphocytic leukemia antigen – CALLA, membrane metallo-endopeptidase – MME, enkefalinase) is a 100-kDa cell surface zinc metalloprotease, cleaving peptide bonds on the N-terminus of hydrophobic amino acids and inactivating multiple physiologically active peptids. CD10 is expressed on various normal cell types, including lymphoid precursor cells, germinal center B lymhocytes, and some epithelial cells, and its expression level serves as a marker for diagnostics of many carcinomas. CD10 is also a differentiation antigen for early B-lymphoid progenitors in the B-cell differentiation pathway and has a key role in regulation of growth, differentiation and signal transduction of many cellular systems.

Specyficzność

The antibody MEM-78 reacts with an extracellular epitope CD10 antigen (CALLA - Common acute lymphatic leukemia antigen), a 100 kDa type II integral membrane protein.

Immunogen

NALM-6 human pre-B cell line

Postać fizyczna

Stabilizing phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide

Uwaga dotycząca przygotowania

Purified antibody is conjugated with activated tandem dye of allophycocyanin-cyanine 7 (APC-Cy7) under optimum conditions and unconjugated antibody and free fluorochrome are removed by size-exclusion chromatography.

Przechowywanie i stabilność

Store at 2-8°C. Protect from prolonged exposure to light. Do not freeze.

Inne uwagi

The antibody solution should be gently mixed before use.

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Informacja o środkach bezpieczeństwa

• Kod klasy składowania: 12 - Non Combustible Liquids
• Klasa zagrożenia wodnego (WGK): WGK 1
• Temperatura zapłonu (°F): Not applicable
• Temperatura zapłonu (°C): Not applicable