SAB4504378

Anti-phospho-DARPP-32 (pThr³⁴) antibody produced in rabbit

affinity isolated antibody

• Kod UNSPSC: 12352203
• NACRES: NA.41

Właściwości

• pochodzenie biologiczne: rabbit
• białko sprzężone: unconjugated
• forma przeciwciała: affinity isolated antibody
• rodzaj przeciwciała: primary antibodies
• klon: polyclonal
• Postać: buffered aqueous solution
• masa cząsteczkowa: antigen 22 kDa
• reaktywność gatunkowa: mouse, rat, human
• stężenie: ~1 mg/mL
• metody: ELISA: 1:10000; immunofluorescence: 1:100-1:500; immunohistochemistry: 1:50-1:100; western blot: 1:500-1:1000
• numer dostępu NCBI: Q9UD71
• numer dostępu UniProt: Q9UD71
• Warunki transportu: wet ice
• temp. przechowywania: −20°C
• docelowa modyfikacja potranslacyjna: phosphorylation (pThr34)
• informacje o genach: human ... PPP1R1B(84152)

Opis

Opis ogólny

PPP1R1B (protein phosphatase 1 regulatory inhibitor subunit 1B)/DARPP32 (dopamine- and cAMP-regulated phosphoprotein of molecular weight 32 kDa) encodes two transcripts which are further translated into two DARPP-32 protein isoforms, full length (fl)-DARPP-32 and truncated (t)-DARPP. It is located on human chromosome 17q12.

Immunogen

The antiserum was produced against synthesized peptide derived from human DARPP-32 around the phosphorylation site of Thr34.

Immunogen Range: 18-67

Działania biochem./fizjol.

PPP1R1B (protein phosphatase 1 regulatory inhibitor subunit 1B)/DARPP32 (dopamine- and cAMP-regulated phosphoprotein of molecular weight 32 kDa) is considered as an inhibitor of phosphate-1 (PP-1) protein. This protein is associated with working memory and emotion processing.

Cechy i korzyści

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Postać fizyczna

Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Oświadczenie o zrzeczeniu się odpowiedzialności

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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Informacja o środkach bezpieczeństwa

• Kod klasy składowania: 10 - Combustible liquids
• Klasa zagrożenia wodnego (WGK): WGK 1
• Temperatura zapłonu (°F): Not applicable
• Temperatura zapłonu (°C): Not applicable