SAB4504066

Anti-phospho-SGK (pSer⁷⁸) antibody produced in rabbit

affinity isolated antibody

• Kod UNSPSC: 12352203
• NACRES: NA.41

Właściwości

• pochodzenie biologiczne: rabbit
• białko sprzężone: unconjugated
• forma przeciwciała: affinity isolated antibody
• rodzaj przeciwciała: primary antibodies
• klon: polyclonal
• Postać: buffered aqueous solution
• masa cząsteczkowa: antigen 48 kDa
• reaktywność gatunkowa: human, rat, mouse
• stężenie: ~1 mg/mL
• metody: ELISA: 1:10000; western blot: 1:500-1:1000
• numer dostępu NCBI: O00141
• numer dostępu UniProt: O00141
• Warunki transportu: wet ice
• temp. przechowywania: −20°C
• docelowa modyfikacja potranslacyjna: phosphorylation (pSer78)
• informacje o genach: human ... SGK1(6446)

Opis

Opis ogólny

The serum and glucocorticoid-regulated kinase (Sgk1) is a member of the AGC kinase family. It is located on human chromosome 6q23. Sgk1 is an aldosterone-induced protein kinase.

Immunogen

The antiserum was produced against synthesized peptide derived from human SGK around the phosphorylation site of Ser78.

Immunogen Range: 41-90

Działania biochem./fizjol.

The serum- and glucocorticoid-regulated kinase (Sgk1) controls ENaC (expressed renal epithelial Na⁺ channel) by mineralocorticoids. SGK1 controls p27 phosphorylation upon the activation by mTOR-Raptor. This gene is essential to control blood pressure and hypertension in man.

Cechy i korzyści

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Postać fizyczna

Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Oświadczenie o zrzeczeniu się odpowiedzialności

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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Informacja o środkach bezpieczeństwa

• Kod klasy składowania: 10 - Combustible liquids
• Klasa zagrożenia wodnego (WGK): WGK 1
• Temperatura zapłonu (°F): Not applicable
• Temperatura zapłonu (°C): Not applicable