SAB4502201

Anti-PLAGL1 antibody produced in rabbit

affinity isolated antibody

• Synonim(y): LOT-1, Lost on transformation 1, Pleiomorphic adenoma-like protein 1, Tumor supressor ZAC, Zinc finger protein PLAGL1
• Kod UNSPSC: 12352203
• NACRES: NA.41

Właściwości

• pochodzenie biologiczne: rabbit
• białko sprzężone: unconjugated
• forma przeciwciała: affinity isolated antibody
• rodzaj przeciwciała: primary antibodies
• klon: polyclonal
• Postać: buffered aqueous solution
• masa cząsteczkowa: antigen 50 kDa
• reaktywność gatunkowa: human
• stężenie: ~1 mg/mL
• metody: ELISA: 1:10000; western blot: 1:500-1:1000
• numer dostępu NCBI: Q9UM63
• numer dostępu UniProt: Q9UM63
• Warunki transportu: wet ice
• temp. przechowywania: −20°C
• docelowa modyfikacja potranslacyjna: unmodified
• informacje o genach: human ... PLAGL1(5325)

Opis

Opis ogólny

The gene PLAGL1 (pleiomorphic adenoma-like protein 1), PLAGL2 and PLAG1 form a subfamily of PLAG family of zinc finger proteins that recognize DNA and RNA. The three members share similarity at the amino-terminal, but are functionally different, varying in their DNA binding capacities. The gene is mapped to human chromosome 6q24.2, a region implicated in several cancers.

Immunogen

The antiserum was produced against synthesized peptide derived from human PLAGL1.

Immunogen Range: 311-360

Działania biochem./fizjol.

The maternally-imprinted gene, PLAGL1 (pleiomorphic adenoma-like protein 1), functions as an oncogene as well as a tumor suppressor depending on the cell context. It has been found to exhibit anti-proliferative properties and regulate apoptosis and cell-cycle arrest via p53.

Cechy i korzyści

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Postać fizyczna

Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

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Informacja o środkach bezpieczeństwa

• Kod klasy składowania: 10 - Combustible liquids
• Klasa zagrożenia wodnego (WGK): nwg
• Temperatura zapłonu (°F): Not applicable
• Temperatura zapłonu (°C): Not applicable