SAB4501174
Anti-Connexin 43 Antibody
rabbit polyclonal
Synonim(y):
CX43, CXA1, CXN-43, Connexin 43, Gap junction 43 kDa heart protein
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About This Item
Kod UNSPSC:
12352203
NACRES:
NA.41
Polecane produkty
product name
Anti-Connexin 43 antibody produced in rabbit, affinity isolated antibody
pochodzenie biologiczne
rabbit
Poziom jakości
białko sprzężone
unconjugated
forma przeciwciała
affinity isolated antibody
rodzaj przeciwciała
primary antibodies
klon
polyclonal
Postać
buffered aqueous solution
masa cząsteczkowa
antigen 43 kDa
reaktywność gatunkowa
mouse, human, rat
stężenie
~1 mg/mL
metody
ELISA: 1:20000
western blot: 1:500-1:1000
numer dostępu NCBI
numer dostępu UniProt
Warunki transportu
wet ice
temp. przechowywania
−20°C
docelowa modyfikacja potranslacyjna
unmodified
informacje o genach
human ... GJA1(2697)
Opis ogólny
Connexin 43 belongs to the connexin protein family that forms gap junction. This protein is highly expressed in neurons and radial glia during development and in astrocytes in adult brains.
Connexin 43 belongs to the connexin protein family that forms gap junction. This protein is highly expressed in neurons and radial glia during development and in astrocytes in adult brains.
Immunogen
The antiserum was produced against synthesized peptide derived from human Connexin 43.
Immunogen Range: 332-381
Immunogen Range: 332-381
Zastosowanie
Anti-Connexin 43, C-Terminal antibody produced in rabbit has been used in flow cytometry.
Działania biochem./fizjol.
In rodents, connexin-43 (Cx-43) shows specific temporal patterns of expression during brain development. Experimental studies reveal that, connexin-43 expression increases in the brain during sheep ontogenesis.This protein might play a crucial role in neuronal migration as it resides in radial glial fibers which are closely associated with migrating neurons. It is also involved in transmembrane NAD+ transport. connexin-43, which is an element of gap junction, helps in cell–cell communication. Cx-43 is known to induce [Ca2+] i burst phenomenon in uterine artery endothelial cells (UAECs).
Cechy i korzyści
Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more.
Postać fizyczna
Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Oświadczenie o zrzeczeniu się odpowiedzialności
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
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Kod klasy składowania
10 - Combustible liquids
Klasa zagrożenia wodnego (WGK)
nwg
Temperatura zapłonu (°F)
Not applicable
Temperatura zapłonu (°C)
Not applicable
Certyfikaty analizy (CoA)
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Dokumenty związane z niedawno zakupionymi produktami zostały zamieszczone w Bibliotece dokumentów.
S Bruzzone et al.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology, 15(1), 10-12 (2000-12-02)
A previously unrecognized passive transport for pyridine dinucleotides has been described recently in the plasmamembrane of several mammalian cells. Despite elucidation of some functional and kinetic properties of this transport system, it is still undefined at the molecular level. Therefore
B Nadarajah et al.
The Journal of neuroscience : the official journal of the Society for Neuroscience, 17(9), 3096-3111 (1997-05-01)
Gap junctions are membrane channels that mediate the direct passage of ions and molecules between adjacent cells. Recent tracer coupling and optical recording studies have revealed the presence of gap junction-mediated communication between neurons during neocortical development. We have visualized
Grazyna B Sadowska et al.
Brain research, 1255, 51-56 (2008-12-23)
Gap junctions are specialized membrane structures that mediate intercellular communication and facilitate passage of ions and small molecules between adjacent cells. Connexins comprise a multigene family of transmembrane proteins that form gap junctions. Connexin-32 and connexin-43 are among the most
Fu-Xian Yi et al.
Biology of reproduction, 82(1), 66-75 (2009-09-11)
Endothelium-mediated vasodilation is specifically enhanced in uterine circulation during pregnancy, and production of nitric oxide (NO) is increased in response to a wide array of agonists. Uterine artery endothelial cells from nonpregnant (NP-UAECs) or pregnant (P-UAECs) ewes maintained in culture
Dongdong Yuan et al.
BMC anesthesiology, 21(1), 267-267 (2021-11-05)
Opioids have been identified by the World Health Organization to be 'indispensable for the relief of pain and suffering'. Side-effects, such as nausea, vomiting, postoperative delirium, and effects on breathing, of opioids have been well investigated; however, the influence of
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