RAB1122

Mouse EPO ELISA Kit

for cell culture supernatants, plasma, and serum samples

• Kod UNSPSC: 41116158
• NACRES: NA.32

Właściwości

• reaktywność gatunkowa: mouse
• opakowanie: kit of 96 wells (12 strips x 8 wells)
• metody: ELISA: suitable
• moc wejściowa: sample type cell culture supernatant(s); sample type plasma; sample type serum sample(s)
• assay range: inter-assay cv: <12%; intra-assay cv: <10%; sensitivity: 1.5 pg/ml
• metoda wykrywania: colorimetric
• Warunki transportu: wet ice
• temp. przechowywania: −20°C
• informacje o genach: mouse ... Epo(13856)

Opis

Opis ogólny

This ELISA antibody pair detects Mouse Erythropoietin (EPO)

Zastosowanie

For research use only. Not for use in diagnostic procedures.
Please refer to the attached Protocolfor details.

Działania biochem./fizjol.

Erythropoietin (EPO) is a glycoprotein hormone which is essential for the proliferation of erythropoietic progenitors to produce red blood cells (RBCs). Peritubular fibroblast in kidney cortex is the primary site for EPO production in adults, though spleen, bone marrow and liver contribute to the production. In fetus, liver is the primary site for EPO production. Additionally, EPO functions in some cytoprotective activities like, antiapoptotic, antioxidant, and anti-inflammatory responses. Hypoxia inducible factors upregulate EPO expression. EPO expression increases with decreased hemoglobin concentration in few cases of anemia. Decreased production of EPO is the cause of anemia in chronic kidney diseases. Circulating endogenous antibodies to EPO (anti-EPO) is the cause of anemia in multiple diseases like human immunodeficiency virus (HIV) infection, hepatitis C virus infection, systemic lupus erythematosus. Gain-of-function polymorphism in EPO causes familial erythrocytosis.

Inne uwagi

A sample Certificate of Analysis is available for this product. Please type the word sample in the text box provided for lot number.

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Informacja o środkach bezpieczeństwa

• Piktogramy: GHS05
• Hasło ostrzegawcze: Warning
• Zwroty wskazujące rodzaj zagrożenia: H290
• Zwroty wskazujące środki ostrożności: P234 - P390
• Klasyfikacja zagrożeń: Met. Corr. 1
• Kod klasy składowania: 8A - Combustible corrosive hazardous materials
• Temperatura zapłonu (°F): Not applicable
• Temperatura zapłonu (°C): Not applicable