RAB0219

Human sICAM1 ELISA Kit

for serum, plasma, cell culture supernatant and urine

• Kod UNSPSC: 41116158
• NACRES: NA.32

Właściwości

• reaktywność gatunkowa: human
• opakowanie: kit of 96 wells (12 strips x 8 wells)
• metody: ELISA: suitable; capture ELISA: suitable
• moc wejściowa: sample type urine; sample type plasma; sample type serum; sample type cell culture supernatant(s)
• assay range: inter-assay cv: <12%; intra-assay cv: <10%; sensitivity: 150 pg/mL; standard curve range: 0.313-20 ng/mL
• metoda wykrywania: colorimetric
• Warunki transportu: wet ice
• temp. przechowywania: −20°C
• informacje o genach: human ... ICAM1(3383)

Opis

Opis ogólny

The Human sICAM-1 ELISA (Enzyme-Linked Immunosorbent Assay) kit is an in vitro enzyme-linked immunosorbent assay for the quantitative measurement of human soluble ICAM-1 in serum, plasma, cell culture supernatants and urine.

Immunogen

Recombinant Human ICAM1

Zastosowanie

For research use only. Not for use in diagnostic procedures.
Human sICAM1 (intercellular adhesion molecule 1) ELISA Kit has been used for measuring sICAM1 levels in the endothelial cell-conditioned medium.

For research use only. Not for use in diagnostic procedures.
Please refer to the attached General ELISA KIT Procedure (sandwich, competitive & Indirect ELISA)

Działania biochem./fizjol.

The expression of ICAM1 (intercellular adhesion molecule 1) is strongly increased by Interleukin-1 (IL-1) and interferon (IFN)-γ. It is expressed on lymphoid cells where it is required for phorbol ester-induced aggregation. It participates in LFA-1-dependent NK cell stimulation through its attachment to actin cytoskeleton through α-actinin or ezrin. It also acts as the receptor for rhinovirus, a common cold virus, and Plasmodium falciparum. Soluble ICAM-1 (sICAM1) levels are elevated in pregnant women with gestational diabetes mellitus (GDM), which is an outcome of endothelial cell activation and dysfunction. In addition, ICAM-1 also has an essential role in binding circulating leukocytes to the blood vessel wall and trans-endothelial migration to vascular intima. Meta-analysis of case-control studies show that rs1799969 polymorphism in ICAM-1 gene is linked with increased susceptibility to cancer. sICAM1 might act as a biomarker for unipolar and bipolar patients.

Inne uwagi

A sample Certificate of Analysis is available for this product.
Please type the word sample in the text box provided for lot number.

This page may contain text that has been machine translated.

Elementy zestawu są też dostępne oddzielnie

• RABELADA ELISA 1X Assay/Sample Diluent Buffer A (Item D1)
• RABELADB ELISA 5X Assay/Sample Diluent Buffer B (Item E1)
• RABSTOP3 ELISA Stop Solution (Item I)
• RABTMB3 ELISA Colorimetric TMB Reagent (HRP Substrate, Item H)
• RABWASH4 20X Wash Buffer (Item B)

Informacja o środkach bezpieczeństwa

• Piktogramy: GHS05
• Hasło ostrzegawcze: Warning
• Zwroty wskazujące rodzaj zagrożenia: H290
• Zwroty wskazujące środki ostrożności: P234 - P390
• Klasyfikacja zagrożeń: Met. Corr. 1
• Kod klasy składowania: 8A - Combustible corrosive hazardous materials