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RAB0028

Sigma-Aldrich

Human BMP2 ELISA Kit

for serum, plasma, cell culture supernatant and urine

Synonim(y):

BMP-2, Bone morphogenetic protein 2

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About This Item

Kod UNSPSC:
41116158
NACRES:
NA.32

reaktywność gatunkowa

human

opakowanie

kit of 96 wells (12 strips x 8 wells)

metody

ELISA: suitable
capture ELISA: suitable

moc wejściowa

sample type serum
sample type cell culture supernatant(s)
sample type urine
sample type plasma

assay range

inter-assay cv: <12%
intra-assay cv: <10%
sensitivity: 45 pg/mL
standard curve range: 46.88-3000 pg/mL

metoda wykrywania

colorimetric

Warunki transportu

wet ice

temp. przechowywania

−20°C

informacje o genach

human ... BMP2(650)

Opis ogólny

BMP2 (bone morphogenetic protein 2) is encoded by the gene mapped to human chromosome 20p12.3. The encoded protein belongs to transforming growth factor-β (TGFβ) superfamily. BMP-2 is expressed in heart, lung, and dorsal aorta.
The Human BMP-2 ( Bone morphogenetic proteins-2) ELISA (Enzyme-Linked Immunosorbent Assay) kit is an in vitro enzyme- linked immunosorbent assay for the quantitative measurement of human BMP-2 in serum, plasma, cell culture supernatants and urine.

Immunogen

Recombinant Human BMP2

Zastosowanie

For research use only. Not for use in diagnostic procedures.
Human BMP2 (bone morphogenetic protein 2) ELISA kit has been used for measuring concentrations of BMP in conditioned mouse organoid media.
Please refer to the attached General ELISA KIT Procedure (sandwich, competitive & Indirect ELISA)

Działania biochem./fizjol.

BMP2 (bone morphogenetic protein 2) plays a vital role in the activation of the autonomic lineage-specific basic–helix-loop-helix protein MASH1 (mammalian achaete scute homolog-1) and in the autonomic neurogenesis in neural crest stem cells in vitro. During bone repair, BMP-2 controls the expression of Runt-related transcription factor 2 (Runx2) and Osterix (Osx), thereby enhancing migration, proliferation and osteogenic differentiation of mesenchymal stem cells. In addition to its osteogenic activity, BMP-2 also plays an important role in cardiac morphogenesis. Recombinant human bone morphogenetic protein-2 (rhBMP-2) plays an essential role in pathogenesis of oral squamous cell carcinomas. Mutation in BMP-2 gene is associated with osteoporosis.

Inne uwagi

A sample Certificate of Analysis is available for this product.
Please type the word sample in the text box provided for lot number.
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Elementy zestawu są też dostępne oddzielnie

Numer produktu
Opis
Karta charakterystyki

  • RABELADAELISA 1X Assay/Sample Diluent Buffer A (Item D1)Karta charakterystyki

  • RABELADBELISA 5X Assay/Sample Diluent Buffer B (Item E1)Karta charakterystyki

  • RABSTOP3ELISA Stop Solution (Item I)Karta charakterystyki

  • RABTMB3ELISA Colorimetric TMB Reagent (HRP Substrate, Item H)Karta charakterystyki

  • RABWASH420X Wash Buffer (Item B)Karta charakterystyki

Piktogramy

Corrosion

Hasło ostrzegawcze

Warning

Zwroty wskazujące rodzaj zagrożenia

Zwroty wskazujące środki ostrożności

Klasyfikacja zagrożeń

Met. Corr. 1

Kod klasy składowania

8A - Combustible, corrosive hazardous materials

Klasa zagrożenia wodnego (WGK)

WGK 3


Certyfikaty analizy (CoA)

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