Wszystkie zdjęcia(3)
Kluczowe dokumenty
P2870
Pristane
synthetic, ≥98% (GC)
Synonim(y):
Norphytane, 2,6,10,14-Tetramethylpentadecane
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About This Item
Wzór liniowy:
(CH3)2CH(CH2)3CH(CH3)(CH2)3CH(CH3)(CH2)3CH(CH3)2
Numer CAS:
Masa cząsteczkowa:
268.52
Beilstein:
1720538
Numer WE:
Numer MDL:
Kod UNSPSC:
12352001
Identyfikator substancji w PubChem:
NACRES:
NA.25
Polecane produkty
pochodzenie biologiczne
synthetic
Poziom jakości
Próba
≥98% (GC)
Formularz
liquid
masa cząsteczkowa
268.5
warunki przechowywania
(tightly closed)
kolor
colorless
współczynnik refrakcji
n20/D 1.438 (lit.)
bp
68 °C/0.001 mmHg (lit.)
rozpuszczalność
hexane: miscible 10 % (v/v)
gęstość
0.783 g/mL at 20 °C (lit.)
temp. przechowywania
room temp
ciąg SMILES
CC(C)CCCC(C)CCCC(C)CCCC(C)C
InChI
1S/C19H40/c1-16(2)10-7-12-18(5)14-9-15-19(6)13-8-11-17(3)4/h16-19H,7-15H2,1-6H3
Klucz InChI
XOJVVFBFDXDTEG-UHFFFAOYSA-N
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Opis ogólny
Pristane, also known as norphytane, is a saturated norterpenoid alkane derived from phytane. Its immunological properties are valuable for various applications, serving as an inflammation-inducing agent in tumorigenesis and autoimmune disease induction, facilitating research on conditions like rheumatoid arthritis and lupus. Pristane′s diverse applications span acting as an immunological adjuvant, inducing autoimmune diseases, facilitating monoclonal antibody production, and serving as an energy source, making it a valuable asset in biochemical research, cell culture, and molecular biology.
Zastosowanie
Pristane also acts as an immunological adjuvant for generating monoclonal antibodies in mouse ascites and finds use as a biological marker. Additionally, pristane can also be used as the primary carbon and energy source for the growth of a bacterial strain, coryneform soil isolate. Its distinctive ability to induce plasmacytomas is particularly valuable for studying B-cell tumors like Burkitt′s lymphoma.
It is commonly used for priming animals, leading to granulomatous inflammation and disruption of local lymphatic drainage, resulting in increased ascitic yields. It has been used to induce systemic lupus in mice
It is commonly used for priming animals, leading to granulomatous inflammation and disruption of local lymphatic drainage, resulting in increased ascitic yields. It has been used to induce systemic lupus in mice
Pristane has been used as an inflammation-inducing agent, leading to myeloma development in BALB/c strain mice. It has been used as a rheumatoid arthritis-inducing agent in rats.
Cechy i korzyści
High quality compound suitable for multiple research applications
Inne uwagi
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Hasło ostrzegawcze
Warning
Zwroty wskazujące rodzaj zagrożenia
Zwroty wskazujące środki ostrożności
Klasyfikacja zagrożeń
Eye Irrit. 2 - Skin Irrit. 2
Kod klasy składowania
10 - Combustible liquids
Klasa zagrożenia wodnego (WGK)
WGK 3
Temperatura zapłonu (°F)
>230.0 °F - closed cup
Temperatura zapłonu (°C)
> 110 °C - closed cup
Środki ochrony indywidualnej
Faceshields, Gloves, Goggles, type ABEK (EN14387) respirator filter
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Klienci oglądali również te produkty
Animal Models of Rheumatoid Arthritis (I): Pristane-Induced Arthritis in the Rat.
Tuncel J
PLoS ONE, 11, e0155936-e0155936 (2016)
Increased NHC Cells in the Peritoneal Cavity of Plasmacytoma Susceptible BALB/c Mouse.
Sanchez-Gonzalez B
Mediators of Inflammation, 2015, 313140-313140 (2015)
Marli L Moraes et al.
Journal of nanoscience and nanotechnology, 19(7), 3772-3776 (2019-02-16)
The diagnostics of the autoimmune hemolytic anemia (AIHA), a rare disease caused by autoantibody-induced hemolysis, is still prone to false positives for it is based on visual observation in the so-called Direct Coombs test. In this study, we developed a
M Satoh et al.
Clinical and experimental immunology, 121(2), 399-405 (2000-08-10)
Unlike other agents associated with drug-induced lupus, the isoprenoid alkane pristane induces autoantibodies pathognomonic of lupus, including anti-Sm, anti-dsDNA, and anti-ribosomal P in BALB/c and SJL/J mice. The susceptibility of other strains of mice to pristane-induced lupus is unknown and
K Gadó et al.
Haematologica, 86(3), 227-236 (2001-03-20)
There is no ideal animal model for human multiple myeloma (MM). All the models resemble the human disease in some respect, but none of them fulfils all the criteria of a perfect animal model. The pristane oil (2,6,10,12-tetramethylpentadecane)-induced mouse plasmacytoma
Produkty
Carcinogenesis and Epigenetics
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