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P1138

Sigma-Aldrich

1,2-Distearoyl-sn-glycero-3-phosphocholine

≥99%

Synonim(y):

PC, 1,2-Dioctadecanoyl-sn-glycero-3-phosphocholine, 3-sn-Phosphatidylcholine, 1,2-distearoyl, L-α-Phosphatidylcholine, distearoyl, L-β,γ-Distearoyl-α-lecithin, DSPC, PC(18:0/18:0)

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About This Item

Wzór empiryczny (zapis Hilla):
C44H88NO8P
Numer CAS:
816-94-4
Masa cząsteczkowa:
790.15
Beilstein:
3923978
Numer WE:
212-440-2
Numer MDL:
MFCD00036905
Kod UNSPSC:
12352211
Identyfikator substancji w PubChem:
24898160
NACRES:
NA.25

pochodzenie biologiczne

semisynthetic

Próba

≥99%

Postać

powder

grupa funkcyjna

phospholipid

typ lipidu

phosphoglycerides

Warunki transportu

ambient

temp. przechowywania

−20°C

ciąg SMILES

[O-]P(OCC[N+](C)(C)C)(OC[C@]([H])(OC(CCCCCCCCCCCCCCCCC)=O)COC(CCCCCCCCCCCCCCCCC)=O)=O

InChI

1S/C44H88NO8P/c1-6-8-10-12-14-16-18-20-22-24-26-28-30-32-34-36-43(46)50-40-42(41-52-54(48,49)51-39-38-45(3,4)5)53-44(47)37-35-33-31-29-27-25-23-21-19-17-15-13-11-9-7-2/h42H,6-41H2,1-5H3/t42-/m1/s1

Klucz InChI

NRJAVPSFFCBXDT-HUESYALOSA-N

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Opis ogólny

Non-pyrogenic, well-defined liposomes, loaded with a molecule of choice, are formed by a single hydration step.

Zastosowanie


  • Amantadine interactions with phase separated lipid membranes.: This study explores the interactions between amantadine and phase-separated lipid membranes, providing insights into the role of 1,2-Distearoyl-sn-glycero-3-phosphocholine in membrane structure and function (Kinnun et al., 2024).

  • Design of charge converting lipid nanoparticles via a microfluidic coating technique.: This research designs lipid nanoparticles with charge-converting capabilities using 1,2-Distearoyl-sn-glycero-3-phosphocholine, enhancing drug delivery systems (Zöller et al., 2024).

  • Investigation and Comparison of Active and Passive Encapsulation Methods for Loading Proteins into Liposomes.: The study compares methods for protein encapsulation into liposomes using 1,2-Distearoyl-sn-glycero-3-phosphocholine, advancing drug delivery technologies (Pisani et al., 2023).

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Kod klasy składowania

11 - Combustible Solids

Klasa zagrożenia wodnego (WGK)

WGK 3

Temperatura zapłonu (°F)

Not applicable

Temperatura zapłonu (°C)

Not applicable

Środki ochrony indywidualnej

Eyeshields, Gloves, type N95 (US)

Certyfikaty analizy (CoA)

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Dokumenty związane z niedawno zakupionymi produktami zostały zamieszczone w Bibliotece dokumentów.

Odwiedź Bibliotekę dokumentów

Sweta Modi et al.
Journal of controlled release : official journal of the Controlled Release Society, 162(2), 330-339 (2012-07-18)
Nanoparticulate drug carriers such as liposomal drug delivery systems are of considerable interest in cancer therapy because of their ability to passively accumulate in solid tumors. For liposomes to have practical utility for antitumor therapy in patients, however, optimization of
Antonella Accardo et al.
International journal of nanomedicine, 7, 2007-2017 (2012-05-24)
Drug delivery systems consisting of liposomes displaying a cell surface receptor-targeting peptide are being developed to specifically deliver chemotherapeutic drugs to tumors overexpressing a target receptor. This study addresses novel liposome composition approaches to specifically target tissues overexpressing bombesin (BN)
Pan Li et al.
Journal of controlled release : official journal of the Controlled Release Society, 162(2), 349-354 (2012-07-18)
Ultrasound targeted microbubble destruction (UTMD) was one of the most promising strategies to enhance drug delivery in cancer therapy. Microbubbles (MBs) serve as a vehicle to carry anti-tumor drugs and locally release them when exposed to therapeutic ultrasound, resulting in
Peter J Kueffer et al.
Proceedings of the National Academy of Sciences of the United States of America, 110(16), 6512-6517 (2013-03-29)
The application of boron neutron capture therapy (BNCT) following liposomal delivery of a (10)B-enriched polyhedral borane and a carborane against mouse mammary adenocarcinoma solid tumors was investigated. Unilamellar liposomes with a mean diameter of 134 nm or less, composed of
Saumyabrata Mazumder et al.
PLoS neglected tropical diseases, 5(12), e1429-e1429 (2011-12-30)
Vaccines that activate strong specific Th1-predominant immune responses are critically needed for many intracellular pathogens, including Leishmania. The requirement for sustained and efficient vaccination against leishmaniasis is to formulate the best combination of immunopotentiating adjuvant with the stable antigen (Ag)
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