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Merck

MAK335

Sigma-Aldrich

Succinate Assay Kit

sufficient for 100 colorimetric or fluorometric tests

Synonim(y):

Succinate Quantification Kit

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About This Item

Kod UNSPSC:
12161503
NACRES:
NA.84

zastosowanie

sufficient for 100 colorimetric or fluorometric tests

moc wejściowa

beverage(s)
food(s)
biological sample(s)

metoda wykrywania

colorimetric
fluorometric

powiązane choroby

cardiovascular diseases; immunological diseases

temp. przechowywania

−20°C

Opis ogólny

Succinate, or succinic acid, can be found in all plants and animal tissues. It is an intermediate in the citric acid cycle and plays an important role in intracellular energy generation. Succinate is widely used as a flavoring agent in the food, beverage, and pharmaceutical industries due to its low toxicity.

Zastosowanie

The Succinate Assay Kit may be used for:
  • Diabetes Research
  • Food and Beverage Testing
  • Mitochondrial Disorder Research

Cechy i korzyści

Efficient and Precise: Detect Succinate levels ranging from 10 to 400 μM (colorimetric) and 2 to 40 μM (fluorimetric) in a 30 minute room temperature reaction, providing both convenience and sensitivity.


Compatibility with High-Throughput Systems: Easily incorporate our kit into high-throughput handling systems, ensuring smooth and accurate processing, enhancing efficiency in your laboratory workflow.

Przydatność

Suitable for succinate determination in food, beverage, agricultural products, and other biological samples.

Zasada

The Succinate Assay Kit provides a simple, one step assay for measuring succinate. In this assay succinate is converted to pyruvate which reacts with specific reagents and dye to form a colored product. The color intensity at 570 nm or fluorescence at λex/em = 530/585 nm of the reaction product is directly proportional to succinate concentration in the sample. Linear detection range 10 μM to 400 μM for colorimetric assays and 2 to 40 μM for fluorimetric assays.

Inne uwagi

For additional information on our range of Biochemicals, please complete this form.
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Kod klasy składowania

10 - Combustible liquids


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Dokumenty związane z niedawno zakupionymi produktami zostały zamieszczone w Bibliotece dokumentów.

Odwiedź Bibliotekę dokumentów

Sulagna Bhattacharya et al.
EBioMedicine, 68, 103418-103418 (2021-06-09)
We have previously described an evolutionarily selected Tibetan prolyl hydroxylase-2 (PHD2D4E;C127S) variant that degrades the hypoxia-inducible factor (HIFα) more efficiently and protects these highlanders from hypoxia-triggered elevation in haemoglobin concentration. High altitude is known to cause acute mountain sickness (AMS)
Nishith M Shrimali et al.
EBioMedicine, 73, 103672-103672 (2021-11-06)
Phospho-Akt1 (pAkt1) undergoes prolyl hydroxylation at Pro125 and Pro313 by the prolyl hydroxylase-2 (PHD2) in a reaction decarboxylating α-ketoglutarate (αKG). We investigated whether the αKG supplementation could inhibit Akt-mediated activation of platelets and monocytes, in vitro as well as in

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