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Merck

M8645

Sigma-Aldrich

Anti-Mouse IgG (whole molecule) antibody produced in goat

affinity isolated antibody, lyophilized powder

Synonim(y):

Goat Anti-Mouse IgG, Goat IgG Antibody

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About This Item

Numer MDL:
Kod UNSPSC:
12352203
NACRES:
NA.46

pochodzenie biologiczne

goat

Poziom jakości

białko sprzężone

unconjugated

forma przeciwciała

affinity isolated antibody

rodzaj przeciwciała

secondary antibodies

klon

polyclonal

Formularz

lyophilized powder

metody

Ouchterlony double diffusion: suitable

temp. przechowywania

2-8°C

docelowa modyfikacja potranslacyjna

unmodified

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Opis ogólny

IgG is the main antibody type found in plasma and extracellular fluid and is expressed on B cell membrane.
Immunoglobulin G (IgG) belongs to the immunoglobulin family and is a widely expressed serum antibody. An immunoglobulin has two heavy chains and two light chains connected by a disulfide bond. It mainly helps in immune defense. It is a glycoprotein. IgG is a major class of immunoglobulin. Mouse consists of five immunoglobulin classes- IgM, IgG, IgA, IgD and IgE. Mouse IgG is further divided into five classes- IgG1, IgG2a, IgG2b and IgG3.

Immunogen

IgG purified from pooled normal mouse serum.

Zastosowanie

Anti-mouse IgG (whole molecule) antibody (diluted 1:20) can be used in Indirect immunofluorescence. It can also be used as a secondary antibody in western blotting to release NC1 domain of type IV collagen. Further, it can also be used in enzyme immunoassays (50 μgram) .
Anti-mouse IgG (whole molecule) antibody (diluted 1:20) can be used in:
  • indirect immunofluorescence
  • western blotting to release NC1 domain of type IV collagen
  • enzyme immunoassays (50 μgram)

Działania biochem./fizjol.

IgG regulates several functions such as phagocytosis and hence plays a pivotal role in facilitating cytological immune responses. Anti-mouse IgG (whole molecule) antibody can be used in T cell proliferation assays. It can also be used in Ouchterlony Double Diffusion and immunoelectrophoresis. Goat anti- mouse IgG (whole molecule) antibody reacts specifically with mouse IgG subclasses IgG1, IgG2a, IgG2b and IgG3. The product has also shown no reactivity to human serum proteins.
Immunoglobulin G (IgG) participates in hypersensitivity type II and type III reactions. IgG helps in opsonization, complement fixation and antibody dependent cell mediated cytotoxicity.

Inne uwagi

Antibody adsorbed with human serum proteins

Postać fizyczna

Lyophilized from 0.01 M sodium phosphate, 0.015 M sodium chloride, pH 7.2

Rekonstytucja

Reconstitute with 1 mL of 0.135 M sodium chloride.

Oświadczenie o zrzeczeniu się odpowiedzialności

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
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Odwiedź Bibliotekę dokumentów

E M Rust et al.
The Journal of clinical investigation, 103(10), 1459-1467 (1999-05-20)
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T Keeley et al.
Zoo biology, 31(3), 275-290 (2011-03-16)
The Vancouver Island marmot (Marmota vancouverensis; VIM) is one of North America's most endangered species with fewer than 150 individuals remaining in the wild. A captive breeding program was established across four facilities in Canada as an insurance population and
Molecular Genetics of Immunoglobulin, 17 (1987)
The Laboratory Rat (2005)
C S von Bartheld et al.
The Journal of neuroscience : the official journal of the Society for Neuroscience, 20(2), 736-748 (2000-01-13)
Anterograde axonal transport of neurotrophins has been demonstrated recently, but to date such transport has only been shown for brain-derived neurotrophic factor and no other endogenous neurotrophin. Endogenous neurotrophin-3 (NT-3) protein is present in the ganglion cell layer of the

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