M6760

Myricetin

≥96.0%, crystalline

• Synonim(y): 3,3′,4′,5,5′,7-Hexahydroxyflavone, Cannabiscetin, Myricetol
• Wzór empiryczny (zapis Hilla): C₁₅H₁₀O₈
• Numer CAS: 529-44-2
• Masa cząsteczkowa: 318.24
• Beilstein: 332331
• Numer WE: 208-463-2
• Numer MDL: MFCD00006827
• Kod UNSPSC: 12352202
• Identyfikator substancji w PubChem: 24278566
• NACRES: NA.77

Właściwości

• Poziom jakości: 100
• Próba: ≥96.0%
• Postać: crystalline
• mp: >300 °C (lit.)
• rozpuszczalność: absolute ethanol: 10 mg/mL, clear to slightly hazy, yellow to very deep greenish-yellow
• ciąg SMILES: Oc1cc(O)c2C(=O)C(O)=C(Oc2c1)c3cc(O)c(O)c(O)c3
• InChI: 1S/C15H10O8/c16-6-3-7(17)11-10(4-6)23-15(14(22)13(11)21)5-1-8(18)12(20)9(19)2-5/h1-4,16-20,22H
• Klucz InChI: IKMDFBPHZNJCSN-UHFFFAOYSA-N
• informacje o genach: human ... CYP1A2(1544) ; mouse ... Hexa(15211) ; rat ... Il4(287287) , Tnf(24835)

Opis

Zastosowanie

Myricetin has been used:

• to investigate its effect on end product (AGE)- bovine serum albumin mediated phosphorylation of mitogen-activated protein kinase(ERK1)
• as a standard for the quantification of phenolics from noni plant extracts using high performance liquid chromatography(HPLC)
• as a standard for characterization of phenolic compounds from Hibiscus sabdariffa using ultra-high performance liquid chromatography(UHPLC)

Działania biochem./fizjol.

Myricetin is a naturally occurring flavonol with antioxidant property. It displays moderate membrane permeability and it degrades rapidly at elevated pH. Myricetin is one of the major flavonoid present in edible plants and has anticarcinogenic and antimutagenic functionality. It comprises of two benzene rings A and B. Ring B intercalates with nucleotide staking and inhibits bacterial DNA synthesis. Myricetin elicits protective function against oxidative stress generated by tert-butylhydroperoxide (t-BHP) in diabetic rat and improves glutathione peroxidase (GPx) and xanthine oxidase (XO) enzyme activity. It also lowers the glycation of low-density lipoprotein.

This page may contain text that has been machine translated.

Informacja o środkach bezpieczeństwa

• Kod klasy składowania: 11 - Combustible Solids
• Klasa zagrożenia wodnego (WGK): WGK 3
• Temperatura zapłonu (°F): Not applicable
• Temperatura zapłonu (°C): Not applicable
• Środki ochrony indywidualnej: Eyeshields, Gloves, type N95 (US)