M0418
Melanin
BioReagent, Synthetic, suitable for cell culture
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About This Item
Polecane produkty
pochodzenie biologiczne
synthetic
linia produktu
BioReagent
Próba
≥97% (TLC)
Formularz
powder
metody
cell culture | mammalian: suitable
rozpuszczalność
1 N NH4OH: 20 mg/mL
temp. przechowywania
−20°C
InChI
1S/C18H10N2O4/c1-5-13-9-7(3-19-13)12-10-8(11(9)17(23)15(5)21)4-20-14(10)6(2)16(22)18(12)24/h3-4,19-20H,1-2H3
Klucz InChI
XUMBMVFBXHLACL-UHFFFAOYSA-N
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Opis ogólny
Melanin is a distinctive class of pigment found in animals, plants, bacteria, and fungi. It is an amorphous polymer formed by the polymerization of phenolic and indolic compounds.
Zastosowanie
Melanin has been used:
- to incubate normal human keratinocytes for Masson-Fontana staining
- as a standard in the determination of melanin content in normal human epidermal melanocytes and immortalized human keratinocytes
- as an absorber to mimic human skin or melanocytic nevi and melanoma
Działania biochem./fizjol.
Melanin plays a role in camouflage and energy harvesting. It also helps in protection against ionizing UV radiations, protection against biotic factors such as host defense against pathogens, and abiotic factors like heat, cold and osmotic stress. Melanin acts as a potent cation chelator and is a component of several photoprotective creams as it facilitates free radical scavenging activity. Melanin may be useful as a photo protectant in cell culture.
Uwaga dotycząca przygotowania
Prepared by oxidation of tyrosine with hydrogen peroxide.
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Kod klasy składowania
11 - Combustible Solids
Klasa zagrożenia wodnego (WGK)
WGK 1
Temperatura zapłonu (°F)
Not applicable
Temperatura zapłonu (°C)
Not applicable
Środki ochrony indywidualnej
Eyeshields, Gloves, type N95 (US)
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